alcohol symposium Flashcards
alcohol mortality 16-34yrs
accidents, trauma
SH, suicide
poisoning
alcohol mortality 34-64yrs
alcohol related liver disease
alcohol mortality 64yrs+
alcohol related cancer
alcohol effects: low doses
euphoria
reduced anxiety
relaxation
sociability
alcohol effects: high doses
intoxication slurred speeh mood instability impaire judgement unsteady unconsciouss
harmful use of alcohol
pattern of use causing damage to mental, physical health
>1mo or repeatedly over 12mo
alcohol dependence
3+ of (for >1mo or repeatedly 12mo) craving, compulsion difficulty controlling use primary inc tolerance physiological withdrawal persistence despite harmful consequences
alcohol withdrawal
tremor N&V weakness agitation anxiety seizures delirium tremens
delirium tremens
confusion, tremor, hallucinations, delusions
delirium tremens; death
CVS collapse infection seizure hyperthermia self injury
alcohol effect on mental health
anxiety depression sleep disruption suicidal thoughts, acts, SH alcoholic hallucinosis morbid jealousy
wernicke’s encephalopathy
thyamine deficiency
confusion, ataxia, nystagmus, alt mental status, opthalmoplegia
korsakoff’s psychosis
following WE impaired recent and remote memory impaired learning disorientated confabulation
screening tools
CAGE
AUDIT
FAST
PAT
management options
education, harm reduction
social work: benefits, housing, child protection
psychological: CBT, group therapy
medications
prevention WE/korsakoff’s
thyamine replacement
medication for alcohol withdrawal
benzodiazapine
chlorodiazepoxide
medication for aversion/detterent
desulfiram
anti-craving medication
acamprostate
naltrexone
nalmefene
alcoholic fatty liver
most heavy drinkers have this
20% progress to cirrhosis
can go back to normal liver with alcohol abstinence
acute alcoholic hepatitis
drinking >6u/day
jaundice w bilirubin >80
high mortality no specific Rx
alcoholic cirrhosis mortality
75% die of liver decompensation
20-25% hepatocellular cancer sequelae
alcoholic ketoacidosis: increased lipolysis
due to inc cortisol and catecholamines
causes abundance free fatty acids which are converted to ketones
alcoholic ketoacidosis: pt has impaired ability to make….
pt has impaired ability to make Glc and metabolise lactate
drive to hypoglycaemia and acidosis