Alcohol Flashcards
What is the daily recommended intake?
14 units
How much alcohol is allowed in pregnancy?
0 in first trimester, 2 onwards
What is described as a dangerous intake? (units)
35 for women
50 for men
How to calculate the no. of units?
% x mls
- 12% bottle of wine: 9 units
- 40% litre of whisky: 40 units
How long does it take to metabolise a unit of alcohol
1 hour
When does delirium tremens peak?
72 hours
Sx of delirium tremens?
Acute confusion, seizures, hallucinations (visual and tactile)
Tx of delirium tremens?
Supportive fluids
Chlordiazepoxide,
Prevent/ treat seizures
Sx of Wernickes encephalopathy
- Confusion
- Ataxia
- Ophthalmoplegia - paralysis of muscles of the eye
Tx of Wernickes encephalopathy
Requires thiamine (B1 / pabrinex)
What can Wernickes encephalopathy lead to?
Korsakoffs syndrome
Sx of Korsakoffs syndrome
- Amnesia - retrograde and anterograde
- Confabulation
- Personality changes
IRREVERSIBLE
Physical problems from alcohol
- Pancreatitis - diabetes - amputation
- Erectile dysfunction
- Liver damage
- Dilated cardiomyopathy
- Anaemia
- Cancer - mouth, oesophagus, liver, breast, bowel
Screening for alcohool
CAGE
AUDIT - 10 point questionnaire
Medications to help with alcohol addiction
Antabuse - disulfiram
Acomprosate - GABA blocker
Naltrexone (specialist centres only)
How does acomproaste work
GABA blocker
SEs of acomprosate
pain or weakness
loss of appetite
nausea
dizziness
anxiety
diarrhoea
itching or sweating
depressed mood
sleep problems (insomnia)
dry mouth
numbness or tingly feeling