Alcohol

Question 1

Level of dependency (SAWDRIN)

Answer 1

• Subjective awareness to compulsion to drink
• Avoidance of withdrawal symptoms by further drinking
• Withdrawal symptoms
• Drink seeking behaviour
• Reinstatement of drinking after period of abstinence
• Increased tolerance
• Narrowing of repertoire

Question 2

Treatment

Answer 2

Disulfram = promotes abstinence - alcohol intake causes severe reaction due to inhibition of acetaldehyde dehydrogenase
Acamproste = reducing craving, known to a weak antagonist of NDMA receptors, improves abstinence in placebo controlled trials