Affective Disorders Flashcards

1
Q

What are mood disorders?

A

Disorders of mental status and function where altered mood is the core feature

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2
Q

What are the psychological symptoms of depression?

A

Change in mood (depression, anxiety, perplexity, anhedonia)

Change in thought content (guilt, hopelessness, worthlessness)

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3
Q

What are the physical symptoms of depression?

A

Change in bodily function (energy, sleep, appetite, libido, constipation, pain)
Change in psychomotor functioning (agitation, retardation)

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4
Q

What are the social symptoms of depression?

A

Loss of interests
Irritability
Apathy
Withdrawal, loss of confidence, indecisive
Loss of concentration, registration and memory

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5
Q

What is anhedonia?

A

Loss of ability to derive pleasure from experience

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6
Q

What is stupor?

A

A state of extreme retardation in which consciousness is intact. The patient stops moving, speaking, eating and drinking

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7
Q

What are the symptoms of somatic syndrome?

A

Marked loss of interest or pleasure in activities that are normally pleasurable
Lack of emotional reactions to events or activities that normally produce an emotional response
Waking 2hrs before the normal time
Depression worse in morning
Objective evidence of psychomotor agitation or retardation
Marked loss of appetite
Weight loss
Marked loss of libido

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8
Q

What is the general criteria for depression?

A

AT LEAST 2 OF:
Depressed mood that is abnormal for most of the day almost everyday for the past 2 weeks, largely uninfluenced by circumstances
Loss of interest or pleasure
Decreased energy or increased fatigability

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9
Q

What is the additional criteria used to assess severity of depression?

A

Loss of confidence or self esteem
Unreasonable feelings of guilt or self reproach or excessive guilt
Recurrent thoughts of death by suicide or any suicidal behaviour
Decreased concentration
Agitation or retardation
Sleep disturbance of any sort
Change in appetite

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10
Q

What is the differential diagnosis for depression?

A
Normal reaction to life event 
SAD 
Dysarthria 
Cyclothymia 
Bipolar 
Stroke, tumour, dementia 
Hypothyroidism, Addison's, hyperparathyroidism 
Infections (influenza, hepatitis, HIV/AIDS) 
Drugs
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11
Q

What is the treatment for depression?

A

Antidepressants
CBT
ECT

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12
Q

What are the different types of antidepressants used to treat depression?

A

Selective serotonin reuptake inhibitors
Tricyclic antidepressants
Monamine oxidase inhibitors

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13
Q

What are the symptoms of hypomania?

A

Lesser degree of mania, no psychosis
Mild elevation of mood or several days on end
Increased energy and activity, marked feeling of wellbeing
Increased sociability, talkativeness, overfamiliarity, increased sexual energy, decreased need for sleep
May be irritable
Concentration reduced, new interests, mild overspending

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14
Q

What are the symptoms of mania?

A

Severe enough to disrupt work and social activities
Elevated mood, increased energy, overactivity, pressure of speech, decreased need for sleep
Disinhibition
Grandiosity
Alteration of senses
Extravagant spending

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15
Q

What is the differential diagnosis of mania?

A
Mixed affective state 
Schizoaffective disorder 
Schizophrenia 
Cyclothymia 
ADHD 
Drugs and alcohol 
Stroke, MS, tumour, epilepsy, AIDS, neurosyphilis 
Cushing's, hyperthyroidism 
SLE
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16
Q

What tools can be used to measure mania?

A

SCID
SCAN
Young mania rating scale

17
Q

What is the treatment for mania?

A

Antipsychotics (Olanzapine, Risperidone, Quetiapine)
Mood stabilisers (Sodium valproate, Lamotrigene, Carbamazepine)
Lithium
ECT

18
Q

What is bipolar disorder?

A

Consists of repeated (2+) episodes of depression and mania or hypomania

19
Q

What are the classification systems that are used to classify mental disorders?

A

ICD-10 (international classification of disease 10th edition)
DSM-5 (diagnostic and statistical manual of mental disorders 5th edition)

20
Q

What is the ICD-10 criteria for depression diagnosis?

A

Last for at least 2 weeks
No hypomanic ir manic episodes in lifetime
Not attributable to psychoactive substance use or organic mental disorder