Aerobic system Flashcards
Sarco
Muscle
Where does the ATP-PC system and glycolysis take place?
Cytosol/sarcoplasm
Glycolysis
Splitting of sugar
- Happens under aerobic and anaerobic conditions (only difference is biproduct)
Aerobic metabolism
From the sarcoplasm to the mitochondria
Lactate dehydrogenase
Lactate into pyruvate and visa versa
Pyruvate + NADH + H⁺ ↔ Lactate + NAD⁺
Where does glycolysis occur?
Sarcoplasm
Citric acid cycle hydrogen carries
NAD to NADH+H
FAD to FADH2
Electron transfer chain
(During glycolysis), hydrogen is released as glucose
More hydrogen is released in the Kreb’s cycle
Hydrogen transported in pairs
Hydrogen released in glycolysis and the Krebs cycle combines with 2 coenzymes
How does pyruvate get to Acetyl CoA?
Removal of CO2 (decarboxylation)
Pyruvate dehydrogenase
TPP helps to stabilise the molecule once it become 2 carbon molecule
Becomes oxidised and CoA is now attached
Electrons transferred from NAD+ to NADH
Name the 8 parts in the Krebs cycle?
Citrate (6)
Isocitrate (5)
Alpha-ketoglutarate (5)
Succinyl CoA (4)
Succinate (4)
Fumarate (4)
Malate (4)
Oxaloacetate (4)
What are FADH2 and NADH used for?
Carrying electrons over from the kreb’s cycle to the ETC
What products are made from one Kreb’s cycle?
2 CO2
3 NADH
1 FADH
1 ATP
Where does the Kreb’s cycle happen?
Mitochondrial matrix
Where does the ETC happen?
Inner membrane of mitochondria
