Adverse drug reactions Flashcards
1
Q
Drugs that cause renal impairment
A
Metformin
ACE inhibitors (expect <20% rise in creatinine when starting)
NSAIDs
ARBs (eg candesartan)
Aminoglycosides eg gentamicin
Aspirin
Stop allopurinol as renally excreted so builds up
NOACs need dose adjustment in renal impairment
2
Q
Drugs that can cause hepatitis
A
Statins
Paracetamol
Rifampicin
3
Q
Drugs that can cause cholestasis
A
Flucloxacillin Nitrofurantoin Co-amoxiclav Steroids Sulphonylureas
4
Q
Drugs that can cause urinary retention
A
Morphine/opiates Benzodiazepines Anticholinergics (mood drugs) NSAIDs CCBs Antihistamines Alcohol (basically drugs that make you sleepy and happy)
5
Q
Drugs that can cause confusion
A
BRAIN DRUGS: Morphine/opiates Metoclopramide Anticholinergics Antipyschotics Antidepressants Anticonvulsants
6
Q
Drugs that can cause agranulocytosis
A
Carbimazole Clozapine Anti inflammatories - sulfasalazine, dipyrone, NSAIDs Anti malarials Trimethoprim Methotrexate
7
Q
Drugs that can cause hyponatraemia
A
SSRIs
ACE inhibitors
Bendroflumathiazide
8
Q
Drugs that can cause hyperkalaemia
A
aldosterone anatagonists eg eplerenone, spironolactone
ciclosporin
ACE inhibitors