Adverse Drug Reaction Flashcards

0
Q

Recycled as an immunosuppressant for leprosy

A

Thalidomide

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1
Q

Recycled as an anti-suicidal drug

A

Clozapine

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2
Q

Extension effect of Aspirin

A

Anti-inflammatory

GU Bleeding/erosions

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3
Q

Side effect of Aspirin

A

Prevention of thrombus formation

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4
Q

Hepatocellular dsyfunction causes adverse reactions with these drugs

A

Phenytoin
Warfarin
Theophylline

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5
Q

Immunosuppressant taken by liver transplant patients that increase potassium by impairment of excretion

A

Cyclosporine

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7
Q

Gell and Coombs classification: beta-lactam anaphylaxis

A

Type I (IgE mediated)

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8
Q

Gell and Coombs classification: penicillin hemolytic anemia

A

Type II (cytotoxic)

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9
Q

Gell and Coombs classification: anti-thymocyte globulin serum sickness

A

Type III (immune complex)

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10
Q

Gell and Coombs classification: topical cell antihistamine contact dermatitis

A

Type IV (cell mediated)

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11
Q

Gell and Coombs classification: sulfonamides morbilliform rash

A

Specific T cell activation

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12
Q

Gell and Coombs classification: Stevens-Johnson syndrome

A

Fas ligand induced

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