Advanced Organic - Amides (7.3) Flashcards
1
Q
What function groups do amides contain?
A
C=O and -NH2
-NH2 attached to this C from C=O
2
Q
How are amides synthesised? What else is formed as a side product?
A
Ammonia + acyl chloride
Side product: NH4Cl
3
Q
How are N-substituted amides synthesised? What else is formed as a side product?
A
Amine + acyl chloride
Side product:
4
Q
What happens in a reaction between amides + water? Give any conditions required for the reaction
A
Conditions: Acid catalyst
They react to produce a carboxylic acid + ammonia
5
Q
What is produced in the dehydration of an amide? Give any conditions required
A
Conditions: P4O10 catalyst
Products: Nitrile + H20
6
Q
What happens in the reduction of an amide? Give any conditions required
A
Conditions: LiAlH4 catalyst
Product: Amine
