Adrenergic Antagonist (blocker) Flashcards
Phentolamine
Reversible, short duration, treat hypertension caused by pheochromocytoma ( tumor in adrenal gland).
Widely used to reverse Local anesthesia with vasoconstrictor.
Phenoxybenzamine
Irreversible, long duration, treat hypertension caused by pheochromocytoma (tumor in adrenal gland)
What are the side effects of non selective alpha antagonists?
May trigger tachycardia and arrhythmia
The Osin family
Praxosin , terazosin, doxazosin, tamsulosin
Prazosin, terazosin, doxazosin
Treatment of hypertension
Tamsulosin
Treatment of enlarged prostate gland
What are the side effects of the alpha antagonist drugs
Orthostatic hypotension, nasal congestion, headache
Yohimbine
A plant alkaloid, treat impotency and stimulate fat loss. May cause anxiety, manic psychosis or suicidal episodes