Adrenergic Antagonist

Question 0

Phenooxybenzamine

Answer 0

Trade names: dibenzyline, fenoxene. Not competitive somewhat alpha-1 selective locker long duration therefore ideal for Pheochromocytoma treatment

Question 1

Phentolamine

Answer 1

Trade name regitine. Competitive nonselective alpha blocker.long-lasting about four hours. Perfusion use. Short-term treatment of pheoChromocytoma hypertension. May also be used with levophed (nore). Given with epinephrine lowers blood pressure.

Question 2

Prazosin

Answer 2

Trade name: Minipress. Used extensively for treatment of hypertension. Alpha 1 blocker

Question 3

Terazosin

Answer 3

Trade name: Hytrin used for hypertension alpha 1 blocker

Question 4

Doxazosin

Answer 4

Trade name cardura. Used for hypertension. Alpha 1 blocker.

Question 5

Tamsulosin

Answer 5

Tradename Flomax. Alpha-1 a blocker with less vascular smooth muscle affect use for BPH (prostate)

Question 6

Alfuzosin

Answer 6

Trade name : Uroxatral. Alpha-1 block or less vascular smooth muscle effect. use for BPH prostate because works on alpha 1 a receptors

Question 7

Beta-adrenergic blockers treat hypertension by

Answer 7

Decreasing cardiac output, decreasing renal renin release, decreases vascular tone

Question 8

Propanolol,timolol,nadolol,

Answer 8

Trade name : Inderal,betimol/istaolol,corgard. Treats angina arrhythmias hyperthyroidism hypertension migraine headaches

Question 9

Esmolol,atenolol,betaxolol,Nebivol,metoprolol,bisoprolol

Answer 9

Trade name:brevibloc,tenormin,Kerlone,bystolic,lopressor/toprol-xl,zebeta
All of these drugs are relatively specific for beta-1 receptors so they are relatively safer to use in asthmatics

Question 10

Acebutolol b1,carteolol, penbutolol,pindolol

Answer 10

Sectral,cartrol,levatol,viskin. these drugs are used for hypertension with bradycardia they possess a mild intrinsic sympathetic activity less cardiac depression less lipid dyscrasias not use for arrhythmias

Question 11

Labetolol, carvedilol

Answer 11

Trade name: trandate,coreg. These drugs are beta and alpha one antagonist. This makes them useful for pregnancy hypertension and congestive heart failure and elderly or black patients whose pressure is poorly controlled

Question 12

Reserpine

Answer 12

Serpasil blocks ATP dependent transport from cytoplasm into storage vesicles which deplete catecholamines.

Question 13

Dosing of beta blockers must be individualized do to

Answer 13

Individual differences in base catecholamine levels catecholamine receptor density and variable cellular response