Adrenergic Antagonist Flashcards
What are a-adrenoblockers
These drugs bind to the a-adreoceptors and prevents the stimulation of norepinehrine
What are the functions of a-adrenoblockers
the dilation of peripheral blood vessels, reducing of peripheral resistance, an increase in venous capacity
a decrease in BP
the improvement of trophy of peripheral tissues
the stimulation of gut motility
the stimulation of the salivary, lacrimal, pancreatic, and respiratory tract
Decrease in urine retention
What are the indication for a- adrenergic blockers
Hypertension
Spasms of peripheral blood vessels (Raynaud’s disease)
Frostbites, trophic ulcers
Pheochromacitoma (diagnostics and treatment)
What are the side effects of a-adrenergic blockers
Headache, vertigo
Hypotension
Weakness
Insomnia
Orthostatic collapse
Tachycardia
vomiting, nausea, diarrhea
rhinitis
List A-adrenergic drugs
Doxazosin= used to treat hypertension and adenoma of prostrate
what are the indications of B-adrenergic blockers
Hypertension
Ischcmic heart disease (angina pectoris, myocardial infarction)
Supraventricular tachyarrthymia
hyperthyroidism
migraine
glaucoma
What are the side effects of B-adrenergic blockers
Bradycardia
Hypotension
increasing heart incompetence
Heart block
Spasm of bronchi
Hypoglycaemia
fatigue
Poor sex drive for men
What are the contraindications for B-adrenergic blockers
Bradycardia
Hypotension
Severe heart failure
Heart block
Bronchial asthma
Ulcerative disease
Diabetes
Disturbance of peripheral blood circulation
pregnancy
List the drugs for B-adrenergic blockers
Metoprolol B1 receptor for the heart
Atenolol B1 receptor for the heart
Propanolol Works on B1 and B2 heart, GI , vessels and bronchi (constrictions)
