ADHD thiings Flashcards

1
Q

what is the MOA of ADHD

A

decreased catecholamines in the synapse

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2
Q

What is the DSM-TV-R criteria for an ADHD diagnosis?

A

6+ symptoms from at least one category (inattentive or hyperactive) for at least 6+ months)
* Maladaptive and INCONSISTENT with developmental level.
* Some symptoms must be present prior to age 12.
* CLEAR FUNCTIONAL IMPAIRMENT IN 2+ SETTINGS. (home and school)

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3
Q

What medications fall under methylphenidates

A

Ritalin
Focalin
Concerta
Quillivant

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4
Q

What medications fall under amphetamines?

A

Adderall
Vyvanse

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5
Q

Methylphenidate MOA

A

block reuptake of catecholamines

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6
Q

amphetamine MOA

A

block reuptake of catecholamines and stimulate dopamine release

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7
Q

Why is XR ideal formualtion for stimulatns

A

reduce adverse SE at the peak and reducing the crash at trough.
Reduces tachyphylaxis (reducing rapid tolerance)

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8
Q

priapism

A

methylphenidates

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9
Q

MAOI use, glaucoma, severe CVD, tourettes, hyperthyroidism

A

CI for stimulants

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10
Q

which stimulant is used more in preschool age

A

methylphenidates

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11
Q

What is the MOA of atomoxetine?

A

SNRI. (Not a controlled substance)

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12
Q

dyspepsia, hepatotoxicity

A

SE of atomoxetine

also has:
CVD
priapism
psychosis/SI
NV ab pain, weight loss, dec appetite

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13
Q

MAOI use, glaucoma, severe CVD, pheochromocytoma

A

CI for atomoxetine

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14
Q

what is first line, second line, third line, and fourth line pharm options for ADHD

A
  1. sitmulants
  2. amoxetine
  3. alpha 2 andrenergic agonists
  4. TCAs
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15
Q

what are the 2 alpha 2 adrenergic agonists

A

XR clonidine
XR guanfacine

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16
Q

SE of sedation and hypotension

A

XR clonidine

17
Q

Cardiotoxicity SE

A

TCAs

18
Q

Child has ADHD but also comorbid psych disorder… what could be used?

A

TCA

19
Q

used to reduce aggressiveness and hyperactivity

A

bupropion

20
Q

blocks reuptake of NE and dopamine MOA

A

bupropion

21
Q

M-CHAT-R/F

A

modified checklist for autism in toddlers

22
Q

treatment for maladaptive behaviors in ASD

A

SSRIs, alpha-andrenergics, antipsychotics

SSRI - specifically risperidone and aripiprazole

23
Q

treatment for anxiety/depression/dysregulated mood in ASD

A

SSRIs

24
Q

treatment for hyperactivity/inattentiveness in ASD

A

stimulatns

25
Q

mutation of MECP2 gene

A

rett syndrome - causes growth deceleration of brain tissue

26
Q

Baby shows deceleration of head growth at 2 months

A

rett syndrome

27
Q

at 14 months, baby Rosa stops using fine motor skills and stops using words that she previously said consistently

A

rett syndrome
deceleration of communication and fine motor skills

28
Q

what are the 2 alpha 2 adrenergic agonists

A

XR clonidine
XR guanfacine