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Therapeutics 3 Kappa Epsilon > ADHD/Peds Psych > Flashcards

ADHD/Peds Psych Flashcards

1
Q

what disorder has BOTH multiple motor and 1+ vocal tics present at some time (not always concurrently)

A

tourettes!

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2
Q

what disorder has single or multiple motor or vocal tics present, but not both

A

persistent/chronic motor or vocal tic disorder…

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3
Q

what tic disorders have to be present for more than 1 year

A

tourettes
and
persistent/chronic motor or vocal tic disorder.

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4
Q

what tic disorder is present for less than 1 year

A

provisional tic disorder

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5
Q

onset of tic disorders happen usually before age _____

A

18

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6
Q 
Treating Tic Disorders:
what drug class should be used?
A

antipsychotics

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7
Q

Treating Tic Disorders:

_____ blockade — efficacious 70 - 90%

A

DA

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8
Q

what antipsychotics are used for treating Tic Disorders?

A

haloperidol
aripiprazole
risperidone/paliperidone (highest DA block)
Orap - pimozide (orphan drug0

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9
Q

why is pimozide of concern? (comparing to haloperidol)

A

QT prolongation

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10
Q

why is haloperidol of concern? (comparing to pimozide)

A

more EPS ADEs

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11
Q

common co=morbidity of tourettes

A

ADHD

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12
Q

______ can exacerbate motor/vocal tic symptoms

A

amphetamine based stimulants

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13
Q

what is ODD stand for

A

oppositional defiant disorder

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14
Q

main criteria groups for ODD

A

angry/irrititable mood
argumenative/defiant behavior
vindictiveness

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15
Q

diagnosis for ODD has to last at least ____

A

6 mos

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16
Q

main criteria groups for CD

A

aggression to ppl/animals
destruction of property
deceitfulness or theft
serious violations of rules

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17
Q

how to treat ODD and CD

A

psycosocial tx = 1st line
drugs 1st choice: stimulants or clonidine/guanfacine!!!

1st line is NOT atypical antipsychotics

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18
Q

for ODD and CD: if atypical antipsychotics tx failure happens at _____ weeks — consider ______ or _____

A

2 weeks

typical antipsychotic or mood stabilizer

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19
Q

1st line option for Separation anxiety disorder

A

combo tx: med monotherapy + psychotherapy

1st line drug option = SSRIs

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20
Q

________ is first line tx for Austism Spectrum Disorder

A

behavioral interventions

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21
Q

what drugs can be used for Autism Spectrum disorder

A

typical antipsychotics: haloperidol

atypical antipsychotics: Aripiprazole and Risperidone

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22
Q

what is CD

A

conduct disorder

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23
Q

for Autism spectrum disorder:

typical or atypical antipsychotics are FDA approved for irritability/aggression

A

atypical (Aripiprazole and Risperidone)

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24
Q

for Autism spectrum disorder:

typical or atypical antipsychotics are used to reduce social isolation/improve anger related behaviors, hyperactivity

A

typical (haloperidol)

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25
if a child has issues with repetitive behaviors --- what drugs can be used
Antipsychotics: haloperidol, risperidone, aripiprazole divalproex (SSRIs done commonly but like like no consistent evidence)
26
what is DMDD
disruptive mood dysregulation disorder
27
atomoxetine has little effect on _______
inattention
28
clonidine and guanfacine has modest effect on ________ and ______
irritability and explosive behavior
29
what are first line tx for DMDD
SSRIs and stimulants
30
first line for pediatric depression
non pharm: CBT!! need group support
31
what antidepressant should be avoided in kids
paroxetine
32
what antidepressant can be used down to kids of 8 yo
fluoxetine
33
what antidepressant can be used for kids starting at age 12
escitalopram
34
for Peds. Bipolar Disorder: | if Bipolar I w/OUT psychosis
Li+ = Drug of choice valproate, CBZ, olanzapine, risperidone, quetiapine too Add 2nd agent after 4 weeks if needed
35
for Peds. Bipolar Disorder: | if Bipolar I w/ psychosis
Li+, Valproate, CBZ WITH any atypical may consider d/c atypical if remission for 12 - 24 mos
36
for Peds. Bipolar Disorder: | if Bipolar I Depressed
1st line Li+ | adjunct w/ Li+ do SSRI or bupropion
37
Atypical Antipsychotics and FDA approvals for Peds.: | Aripiprazole
bipolar irritability w/ autism schizophrenia tourettes
38
Atypical Antipsychotics and FDA approvals for Peds.: | Asenapine
bipolar
39
Atypical Antipsychotics and FDA approvals for Peds.: | lurasidone
schizophrenia | bipolar
40
Atypical Antipsychotics and FDA approvals for Peds.: | Olanzapine
bipolar | schizo
41
Atypical Antipsychotics and FDA approvals for Peds.: | Paliperidone
schizo
42
Atypical Antipsychotics and FDA approvals for Peds.: | quetiapine
bipolar | schizo
43
Atypical Antipsychotics and FDA approvals for Peds.: | which one is ONLY schizophrenia
paliperidone
44
Atypical Antipsychotics and FDA approvals for Peds.: | which one is ONLY biploar
asenapine
45
Atypical Antipsychotics and FDA approvals for Peds.: | which one is for tourettes
aripiprazole
46
Atypical Antipsychotics and FDA approvals for Peds.: | which ones are for irritability for autism
aripiprazole | risperidone
47
Atypical Antipsychotics and FDA approvals for Peds.: | what is the only drug NOT for schizophrenia
asenapine
48
Atypical Antipsychotics and FDA approvals for Peds.: | what is the only drug NOT for bipolar
paliperidone
49
which SSRI is hella hella selective for SERT (like a 7000 fold)
escitalopram
50
AAP Treatment Guidelines for ADHD: | what do you if pt is 4 - 5 years...?
behavioral tx is 1st line!! | can use methylphenidate if behavioral intervention
51
AAP Treatment Guidelines for ADHD: | what do you if pt is 6 - 11 years...?
FDA approved sitmulants/atomoxetine/guanfacine/clonidine and or behavioral therapy (prefer both)
52
AAP Treatment Guidelines for ADHD: | what do you if pt is 12 - 18 years...?
FDA approved sitmulants/atomoxetine/guanfacine/clonidine and or behavioral therapy (prefer both)
53
if getting HA from stimulants --- what do you do
divide dose take with food give analgesic
54
if getting stomach ache from stimulants --- what do you do
take with food | lower dose if possible
55
if getting irritability/jitteriness from stimulants --- what do you do
asses for co-morbid condition reduce dose consider mood stabilizer or atypical antipsychotics
56
which ADHD drug has a rare ADR of priaprism
methylphenidate
57
what ADHD drugs (stimulants or non stimulants) can cause peripheral vasculopathy
stimulants!
58
what drug is a part of daytrana patch
methylphenidate
59
Daytrana Patch: patch applied to out side ____ apply ____ hours prior to needed effects remove after ____ hours
side hip 2 hours 9 hours
60
if pt cant tolerate _____ dont use daytrana
methylphenidate | bc methylphenidate is daytrana
61
atomoxetine has warning for ______ toxicity
liver
62
clonidine or guanfacine is a 3A4 substrate
guanfacine!!
63
T or F: Lithium is v effective in ADHD
false!!! | good for bipolar
64
ADHD and Bipolar are co-morbid: _______ has most evidence in helping ________ is commonly used but not as well studied
CBZ | valproic acid
65
ADHD and Bipolar are co-morbid: | T or F: atypicals can be used as monotherapy
false!! | not ok for ADHD monotherapy
66
Atypical Antipsychotics and FDA approvals for Peds.: | Risperidone
bipolar irritability w/ autism schizophrenia

Therapeutics 3 Kappa Epsilon (20 decks)

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