ADHD Flashcards

1
Q

What are the triad of difficulties on ADHD?

A

Inattention, hyperactivity, impulsivity

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2
Q

What do the triad of ADHD symptoms frequently co-occur with?

A

A cluster of impairing symptoms relating to self regulation

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3
Q

What is the criteria for symptoms to be diagnosed as ADHD?

A

Developmentally inappropriate symptoms
Impair function and pervasive across setting
Longstanding from age 5

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4
Q

How is ADHD considered to be a spectrum?

A

Symptoms cluster on a continuum in the general population

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5
Q

What is the cut off for ADHD symptoms based on?

A

Clinical determination = aided by screening and assessment tools generally based on level of impairment

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6
Q

How does adult ADHD differ from childhood ADHD?

A

Less obvious symptoms of hyperactivity or impulsivity and more inattentive symptoms

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7
Q

What is the impact of childhood ADHD?

A

Significant difficulties parenting children with ADHD
Increased level of home stress and high emotions
Higher likelihood of antisocial behaviours

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8
Q

What does emotional dysregulation in ADHD lead to?

A

Difficulties in peer relationships and reckless or dangerous behaviour

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9
Q

What effect does ADHD have on education?

A

Poor problem solving ability leading to developmentally inappropriate decision making
Significant barrier to learning and potentially exclusion from education

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10
Q

What are the impacts of adult ADHD?

A

Increase in frequency of psychiatric comorbidity
Higher level off criminality and antisocial behaviour
Higher level of substance misuse
Significant impairment in occupational function

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11
Q

What are some issues that untreated ADHD can have on school and family?

A
School = 60% suspended, 32% drop out, lower occupational status
family = 3-5x increase in parental divorce/separation, increased risk of early parenthood
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12
Q

What are some issues of untreated ADHD in society and the healthcare system?

A
Society = 2x increase in substance misuse disorder plus earlier onset, less likely to quit smoking
Healthcare = 50% increase in bike accidents, increased A & E visits, 4x more vehicle crashes
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13
Q

Why do adults present with residual symptoms that don’t meet the diagnostic criteria?

A

Possibly due to improvement in cortical thickness allowing brain to compensate for cognitive deficits

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14
Q

How does ADHD affect families?

A

Hyperactivity tends to aggregate in families

ADHD shows familial clustering both within and across generations

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15
Q

How does a family member having ADHD increase the risk of developing the condition in other family members?

A

60% increased risk in offspring of adults with ADHD

15% increased risk in siblings of children with ADHD

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16
Q

What genes are involved in ADHD?

A

Mainly dopamine and serotonin transporter genes

17
Q

What are some perinatal factors in the development of ADHD?

A

Tobacco/alcohol use during pregnancy
Significant prematurity and perinatal hypoxia
Unusually short/long labour
Foetal distress, eclampsia and low forceps delivery

18
Q

What are some conditions that have ADHD-like symptoms?

A

Foetal alcohol syndrome and use of other illicit substances

19
Q

What are some psychosocial factors that increases risk of ADHD?

A

Severe marital discord, low social class, large family size, parental criminality, maternal mental disorder, maltreatment, emotional trauma

20
Q

What does the typical brainmap pattern in children with ADHD show?

A

Underactive function in the frontal lobe

21
Q

What are the functions of the frontal lobe?

A

Reasoning, planning, impulse control, judgement, initiation of action, social/sexual behaviour, long term memory

22
Q

How are neurotransmitters involved in ADHD?

A

Excessively efficient dopamine removal system = higher concentration of dopamine transporters
Symptoms can be caused by reduction of norepinephrine and serotonin

23
Q

How are children assessed for ADHD?

A

Mainly driven by parents or school
Ideally school observation
Screening and structured diagnostic questionnaires
Exploration of early history and attachment style

24
Q

How are adults assessed for ADHD?

A

Driven by patient = historical concerns are present
Specific adult screening tools available
Comorbidities common
Current clinical picture should fit with ADHD symptoms
Cognitive difficulties and ability to function need to be evaluated

25
What is the diagnostic criteria for children with ADHD?
6 or more symptoms of inattentiveness and/or 6 or more symptoms of hyperactivity and impulsiveness Present before age 5 Reported by parents/school and seen in clinic Symptoms get in the way of daily life
26
What is the diagnostic criteria for adults with ADHD?
5 or more symptoms of inattentiveness and/or 5 or more of hyperactivity and impulsiveness Historical concerns since early age Symptoms have moderate effect on different areas of life
27
What are some psychosocial interventions used to treat children?
Parent training, social skills training, sleep and diet interventions, behavioural classroom management strategies, specific educational interventions
28
When is pharmacological treatment indicated for ADHD?
Only for moderate or severe cases
29
What are the pharmacological treatments for ADHD?
``` 1st line (stimulants) = methylphenidate, dexamfetamine 2nd line (SNRIs) = atomexetine 3rd line (alpha agonists) = clonidine, guanfacine 4th line = antidepressants (imipramine), antipsychotics (resperidone) ```
30
How does methylphenidate work?
Increase dopamine by blocking its transporter
31
How does dexamphetamine work?
Same action as methylphenidate plus increases extracellular norepinephrine and possibly serotonin
32
What is the action of SNRIs?
Increase norepinephrine by blocking its transporter or by reducing sympathetic stimulation