ADHD Flashcards

1
Q

What does ADHD stand for?

A

Attention Deficit Hyperactive Disorder

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2
Q

Three main features of ADHD include:

A
  • Inattention
  • Hyperactive
  • Impulsive
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3
Q

Examples of inattention behaviour?

A
  • Fails to give close attention to details or makes careless mistakes in schoolwork
  • Has difficulty keeping attention during tasks or play
  • Does not seem to listen when spoken to directly
  • Avoids or dislikes tasks that require sustained mental effort (such as schoolwork)
  • Often loses toys, assignments, pencils, books, or tools needed for tasks or activities
  • Often forgetful in daily activities
  • Easily distracted
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4
Q

Examples of hyperactive behaviour?

A
  • Fidget with hands or feet
  • Squirms in seat
  • Runs about or climbs in inappropriate situations
  • Difficulty playing quietly
  • Talks excessively
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5
Q

Examples of impulsive behaviour?

A
  • Blurts out answers before questions have been completed
  • Interrupts conversations
  • Difficulty waiting for their turn
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6
Q

If untreated may lead to:

A
  • high incidence of substance misuse (alcohol and/ or cannabis)
  • educational difficulties
  • relationship problems
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7
Q

ADHD diagnosis must follow extensive mental health assessment by a specialist clinician such as:
In addition the diagnosis should follow a full assessment by an

A
  • Paediatrician
  • Child Psychiatrist
  • Educational +/ or a Clinical Psychologist
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8
Q

Onset of ADHD is usually:

A

Before 3 years old

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9
Q

Duration of ADHD is usually

A

6 months and to a maladaptive level inconsistent with normal development

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10
Q

Non pharmacological treatments of ADHD include:

A
  • psychoeducational methods where the education and advise should be based on treatment offered
  • parent training/ family centred behaviour therapy
  • behavioural interventions (school or pre-school). This will promote social adjustment and reduce hyperactive behaviour
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11
Q

Problem with using pharmacological treatment?

A

Treating symptoms instead of syndromal control

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12
Q

Should not assume that drugs are more hazardous at the younger end of spectrum because:

Therefore, prescribing and subsequent titration should be on a ___/___ dosing range

A

Bioavailability is lower in children because:

  • Drug is distributed in larger extracellular fluid
  • Rapid metabolism

BUT

Drug also crosses BBB more readily .

-mg/kg.

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13
Q

Name two psychostimulant drugs for ADHD

A

Methylphenidate

Dexamphetamine

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14
Q

Name on centrally-acting sympathomimetic used in ADHD

A

Atomoxetine

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15
Q

Pharmacological treatments for ADHD should only be used after _____ _________. AND as part as care package that includes: (3 things)

A

specialist assessment
educational
psychological
behavioural assessment + intervention

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16
Q

Stimulants more affective in treating which feature of ADHD over which other feature?

A

hyperactivity

inattention

17
Q
Stimulants are said to improve:
Overactivity
Attention span
Impulsivity
Aggression
Social Interaction
BUT what may not improve?
A

social skills

general academic achievement

18
Q

Methylphenidate not licensed in children

A

6

19
Q

MOA of methylphenidate?

A

Inhibits reuptake of monamine NTs (e.g DA) into presynaptic neurone therefore increases DA levels at post synaptic receptor sites

20
Q

If no response after _____ at ______ dose(and with assured compliance) decrement and stop.

A

1 month

maximum

21
Q

Adverse effects of methylphenidate:

A

Insomnia
Decreased appetite
Euphoria/ Depression/ Anxiety
Psychosis (rare)

22
Q

Dexamphetamine licensed for children > ___ years

A

3

23
Q

Which pharmacological agent for ADHD has limited abuse potential?

A

Atomoxetine

24
Q

Atomoxetine is licensed for patients aged:

A

6+ years, adolescents and adults

25
Q

Atomexetine MOA:

A

Highly selective inhibitor of the pre-synaptic NE transporter. It has minimal effect on serotonergic or dopaminergic transporters.

26
Q

Psychological response of ADHD is monitored using what rating scale?

A

Connors abbreviated scale