ADHD

Question 1

ADHD symtpoms

Answer 1

~ Hyperactivity
~ Impulsivity
~ Inattention

Question 2

ADHD tx children 5+ & young people

Answer 2

1st line = Methylphenidate (CD2)
2nd line = lisdexmfetamine (CD2)

Alternative = atomoxetine / Guanfacine

Question 3

ADHD tx adults

Answer 3

1st line - Methylphenidate / Lisdexamfetamine
alternative : Atomoxetine

Question 4

Methylphenidate MOA

Answer 4

~ CD2
~ Potent CNS stimulant, increases dopamine + noradrenaline levels

Question 5

Methylphenidate SEs

Answer 5

~ appetite loss
~ Insomnia
~ weight loss
~ increased HR, BP
~ Tics/Tourettes
~ Growth restrictions in children

Question 6

Methylphenidate monitoring

Answer 6

~ Pulse
~ BP
~Appetite
~ Weight/height

Question 7

Methylphenidate contraindications

Answer 7

CVD
Hypothyroidism
Severe HTN
Bipolar disorder
severe depression

Question 8

methylphenidate important info!

Answer 8

PRESCRIBE BY BRAND FOR MODIFIED RELEASE FORMs

Question 9

Dexamfetamine/Lisdexfetamine

Answer 9

CNS stimulant ~ increase dopamine and noradrenaline in brain

Question 10

Dexamfetamine/Lisdexfetamine SEs

Answer 10

~ appetite loss
~ weight loss
~ increased HR, BP
~ Tics/Tourettes
~ Growth restrictions in children

Question 11

Dexamfetamine/Lisdexfetamine signs of overdose

Answer 11

~ wakefulness
~ hyperactivity
~ paranoia
~ hallucinations
~ HTN
~ exhaustion
~ convulsions
~ hyperthermia
~ coma

Question 12

Dexamfetamine/Lisdexfetamine monitoring

Answer 12

starting, dose change and every 6 months
~ Pulse
~ BP
~Appetite
~ Weight/height
~ aggression, depression, psychosis

Question 13

Dexamfetamine/Lisdexfetamine contraindications

Answer 13

CVD
Hypothyroidism
Severe HTN

Question 14

Atomoxetine MOA

Answer 14

Noradrenaline reuptake inhibitor = increased NA levels at synaptic cleft

Question 15

Atomoxetine SEs

Answer 15

~ suicidal ideation
~ Hepatoxicity
pt counsel: report signs of liver disease, N, V, Malaise, dark urine, abdo pain, jaundice
~ QT prolongation