ADH FA

Question 1

how is called ADH?

Answer 1

vasopresin

Question 2

what neurophysin for ADH?

Answer 2

Neurophysin II.

Question 3

what neurophysin for oxytocin?

Answer 3

neurophysin I

Question 4

what nucleus for ADH?

Answer 4

supraoptic

Question 5

what nucleus for oxytocin?

Answer 5

paraventricular

Question 6

posterior pituitary origin?

Answer 6

neuroectoderm

Question 7

where are supraoptic and paraventricular nuclei?

Answer 7

hypothalamus

Question 8

ADH regulates what?2

Answer 8

serum osmolality (V2) and blood pressure (V1)

Question 9

what is primary ADH function?

Answer 9

osmolality regulation

Question 10

osmolality receptor?

Answer 10

V2

Question 11

blood pressure receptor?

Answer 11

V1

Question 12

ADH on serum and urine osmolality?

Answer 12

decr. serum osmol., incr. urine osmol

Question 13

osmol. regulation is based on what?

Answer 13

aquapotin channel insertion in principal cells of collecting duct

Question 14

what renal cells for ADH?

Answer 14

principal cells of collecting duct

Question 15

ADH in central DI?

Answer 15

decreased (decr. production)

Question 16

ADH in Nephr DI?

Answer 16

normal or increased (nera atsako inkstuose, bet production is in tact)

Question 17

ADH analog?

Answer 17

desmopressin

Question 18

use of desmopressin?

Answer 18

central DI or noctunal enuresis

Question 19

why may be nephr DI?

Answer 19

drugs (pvz litis); can be caused due to mutation in V2 receptors.

Question 20

ADH: osmolality vs hypovolemia?

Answer 20

osmolality more important

Question 21

Through which secondary messenger(s) does the ADH-bound V2 receptor propagate its signal?

Answer 21

cAMP

Question 22

cAMP what receptor?

Answer 22

ADH-bound V2 receptor

Question 23

How does ADH increase H2O permeability of the principal cells of the late distal tubule and collecting duct?

Answer 23

Increased aquaporin 2 (AQP2) channels via increased cAMP

Question 24

Through which secondary messenger(s) does the ADH-bound V1 receptor propagate its signal?

Answer 24

IP3/Ca2+

Question 25

IP3/Ca2+

Answer 25

ADH-bound V1 receptor

Question 26

What receptors sense a decrease in plasma volume, providing stimuli to increase ADH secretion?

Answer 26

Baroreceptor

Question 27

baroreceptor in hypovolemia and ADH?

Answer 27

receptors sense a decrease in plasma volume, providing stimuli to increase ADH secretion

Question 28

incr. serum osmolality is sensed where?

Answer 28

sensed by osmoreceptors in the anterior hypothalamus

Question 29

incr. osmolality - what receptors?

Answer 29

osmoreceptors

Question 30

decr. volume - what recetors?

Answer 30

baroreceptors

Question 31

hypovolemia -> baroreceptors -> further signal send where and via what?

Answer 31

information transmitted through the vagus nerve to the hypothalamus

Question 32

What effect does pain, nausea, hypoglycemia, and opiates have on ADH secretion?

Answer 32

increase ADH

Question 33

low volume AND low osmolarity, what ADH?

Answer 33

volume > osmol, and ADH is secreted

Question 34

high volume AND high osmolarity, what ADH?

Answer 34

volume > osmol, and ADH is NOT secreted

Question 35

What effect does alcohol, atrial natriuretic peptide, and α-adrenergic agonists have on ADH secretion?

Answer 35

inhibits ADH

Question 36

Nephrogenic diabetes insipidus is treated with thiazide diuretics. results in decreased Na+ reabsorption and water excretion & increased water reabsorption. Cia mazdaug gaunasi realityvi hipovolemia, todel skatinama vandens reabsorbcija

Answer 36

.