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Biochemistry > Additional > Flashcards

Additional Flashcards

1
Q

VEGF

A

Vascular endothelial GF; Required angiogenic growth factor

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2
Q

Hypoxia > ____ > ____

A

HIF; VEGF

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3
Q

Vasculogenesis

A

Embryonic formation of endothelial cells from the mesoderm layer to form new blood vessels

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4
Q

Angiogenesis

A

New blood vessels from from pre-existing ones formed in the early stages of vasculogenesis

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5
Q

Sprouting angiogenesis

A

tissues with low oxygen produce VEGF which results in blood vessel sprouting

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6
Q

Intussusceptive Angiogenesis

A

Aka splitting angiogenesis; the formation of new vessels by splitting a pre-existing one

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7
Q

FIH

A

Inhibits HIF thus inhibiting angiogenesis

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8
Q

ANG-1

A

Binds to TIE-2 and promotes vessel maturation by stimulating endothelial cells

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9
Q

ANG-2

A

Antagonist of ANG-1; In combination with VEGF, promotes neovascularization (vasculogenesis + angiogenesis)

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10
Q

TIE 2

A

ANG-1/2 can both bind to this; when ANG-2 binds to this along with VEGF resulting in angiogenesis

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11
Q

TIE 1

A

Does not directly bind angiopoietins but promotes angiogenesis

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12
Q

Hemidesmosomes and desmosomes connect to?

A

Intermediate filaments

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13
Q

What filaments are associated with adherens junctions?

A

actin filaments

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14
Q

The adrenal cortex produces

A

mineralcorticoids, glucocorticoids, and androgens/estrogen

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15
Q

The adrenal medulla produces

A

catecholamines

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16
Q

Thyroxine

A

T4

17
Q

Triiodothyronine

A

T3

18
Q

ANG-1 is primarily produced by?

A

Pericytes

19
Q

ANG-2 is primarily produced by?

A

endothelial cells

20
Q

Granulocytes include

A

basophils, eosinophils, neutrophils, macrophages

Biochemistry (10 decks)

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