Addiction Flashcards
Craving
strong desire for drug.
Addiction consists of…
Craving
Withdrawal
Tolerance
Withdrawal
lack of drug causes unhappy symptoms
Tolerance
repeated administrations leads to decreased drug effect.
Pavlovian learning
Conditioning. Link conditional stimulus with unconditional stimulus.
Addiction works because…
The drug mimics the mechanism of something naturally in the brain (regular receptors, processes)
Compensatory response
The conditional response to drug addiction. The brain anticipates the drug and compensates with opposite effect.
Drug administration ritual
Conditional stimulus in addiction. Preparation, setting of drug administration
Morphine effect
Feels good Blocks pain Feels good Decreased blood pressure Warm skin Dry mouth
New ritual, same drug
Lethal because overreaction/ response to drug.
Abstention
Try to go without. Usually relapses.
Extinction
Unlearn. Make ritual not predict the drug.
Dopamine
Pleasure control
Dopamine neuron location
Ventral regimental area (VTA)
Nigrostriatal bundle
Ventral tegmental area projects to nucleus accumbens via this. Activated by addictive drugs.