Acute Renal Failure Flashcards
Acute tubular necrosis (ATN) renal parenchymal failure
Acute tubule-interstitial Nephritis
Acute Renal Failure
Reversible condition characterized by:
• A sudden reduction or cessation of renal function
• Retention of waste products
• Increased UN & creatinine
Acute Renal Failure
Causes of Acute Renal Failure:
Hypoperfusion of kidney
Volume depletion
Impaired cardiac efficiency
Vasodilation
Pre-renal
Causes of Acute Renal Failure:
Actual damage to kidney tissue
Prolonged renal ischemia
Nephrotoxic agents
Infectious process
Intra-renal
Causes of Acute Renal Failure:
Obstruction to urine flow
Urinary tract obstruction
Calculi (stones), tumors
Benign prostatic hyperplasia
Blood clots
Post renal
Phases of Acute Renal Failure: Benign with initial insult and ends when oliguria develops
Onset
Phases of Acute Renal Failure: Initial phase of injury 1-3 days
Onset
Phases of Acute Renal Failure: accompanied by an increase in the serum concentration of substances usually excreted by the kidney
Oliguric Phase
Phases of Acute Renal Failure: Urine output <400 cc/24 hrs for 3 days – 2 weeks
Oliguric Phase
Phases of Acute Renal Failure:
BUN, creatinine
Edema, hypertension
Hyperkalemia
Oliguric Phase
Phases of Acute Renal Failure:
Hyponatremia
Hyperphosphatemia
Metabolic Acidosis
Oliguric Phase
Phases of Acute Renal Failure: signals the improvement of renal function and may take 3 to 12 months
Recovery Phase
Phases of Acute Renal Failure:
Avoid nephrotoxic drugs
May lead to CRF
Recovery Phase
Acute Renal Failure S/Sx: 1st (4)
Irritability
Headache
Anorexia
Tingling of Extremities
Acute Renal Failure S/Sx: ? that can progress to stupor & coma
Lethargy