Acute & Chronic Inflammation Flashcards

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1
Q

When a pathogen attempts to enter the body the first line of defence is:

A

Mechanical barriers such as skin and mucus membranes

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2
Q

When a pathogen enters the body the second line of defence includes:

A

Chemical barriers (enzymes, pH, interferons), natural killer cells, inflammation, phagocytosis, fever.

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3
Q

When a pathogen enters the body the third line of defence includes:

A

Cellular immune response, humoral immune response

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4
Q

What process does a Neutrophil undertake in Cellular Response to kill and digest an invading organism?

A

Phagocytosis

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5
Q

What are the 5 cardinal signs of inflammation?

A

Redness, warmth, swelling, pain, loss of function

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6
Q

Which of the following cells participate in nonspecific defence responses when your body is invaded by microbes?

Select one or more:

a. None of the above
b. natural killer cells
c. Macrophages
d. Neutrophils
e. All of the above

A

All of the above

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7
Q

In the vascular response, what chemical is released from a mast cell that causes vasodilation?

A

Histamine

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8
Q

Which of the following are examples of non-steroidal anti-inflammatory drugs (NSAIDS)?

Select one or more:

a. Prednisolone and Hydrocortisone
b. Ibuprofen and Prednisone
c. Beclomethasone and Budesonide
d. Ibuprofen and Diclofenac

A

Ibuprofen and Diclofenac

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9
Q

All of the following are part of our antigen specific defence mechanisms except:

Select one or more:

a. Lymphocytes
b. Macrophages
c. Acute inflammation
d. Antibody production

A

Acute inflammation

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10
Q

Diseases in which a person’s immune system attacks the person’s own normal tissue are called

A

Autoimmune

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11
Q

The secretion of antibodies by B lymphocytes provides

A

Humoral immunity

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12
Q

Potential side effects of steriod medications such as Prednisone include…

A

a. Adrenal suppression
b. Osteoporosis
c. Immunosuppression Correct

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13
Q

Which of the following statements about the side-effects of corticosteroids is false?

Select one or more:

a. They cause peptic ulcers because they reduce prostaglandin synthesis
b. They cause skin thickening (lichenification)
c. They cause osteoporosis because they reduce the calcium absorption and osteoblast activity
d. They cause hyperglycaemia and should be used by caution by people with diabetes

A

They cause skin thickening (lichenification)

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14
Q

Which of the following is not a phase of the immune response?

Select one or more:

a. Inflammatory mediator release
b. Cortical response
c. Vascular response
d. Cellular response

A

Cortical response

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15
Q

Which of the following is an inflammatory mediator that contributes to pain?

Select one or more:

a. Dopamine Incorrect
b. Prostaglandin
c. Seretonin
d. Boiling water

A

Prostaglandin

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