Acute and Chronic Gastritis

Question 1

Acute Gastritis Etiology?

Answer 1

Drugs (eg, NSAIDs); 
alcohol; 
smoking; 
severe stress; 
systemic infections; 
uremia

Question 2

Chronic Gastritis Etiology?

Answer 2

Type A is an autoimmune disorder

Type B is caused by Helicobacter pylori infection

Question 3

Acute Gastritis gross fx?

Answer 3

subepithelial hemorrhages,
petechiae,
punctate erosion

Question 4

Acute Gastritis histo fx?

Answer 4

neutrophilic infiltration with purulent and hemorrhagic exudate

Question 5

Chronic Gastritis gross fx?

Answer 5

Thickened and reddened rugal folds in fundus (type A) or antrum (type B);

with long-standing disease, mucosa may become atrophic

Question 6

Chronic Gastritis histo fx?

Answer 6

lymphocytic infiltrate in lamina propria;

lymphoid aggregates;

presence of H pylori among microvilli (type B);

hyperplasia of G cells (type A);

presence of intestinal metaplasia or dysplastic cells

Question 7

Acute Gastritis clinical signs?

Answer 7

Anorexia; epigastric pain; nausea; vomiting; hematemesis (coffee ground emesis)

Question 8

Chronic Gastritis Type A clinical signs?

Answer 8

fatigue;

indigestion and diarrhea;

pallor;

mild splenomegaly

Question 9

Chronic Gastritis Type A lab findings?

Answer 9

autoantibodies to parietal cells;

pernicious anemia;

macrocytic anemia;

B12 deficiency;

positive Schilling test

Question 10

Chronic Gastritis Type B clinical signs?

Answer 10

asymptomatic;

associated with peptic ulcer

Question 11

Chronic Gastritis Type B lab findings?

Answer 11

positive H Pylori serology or stool antigen

Question 12

Chronic Gastritis complications?

Answer 12

gastric carcinoma

Question 13

Acute Gastritis Treatment?

Answer 13

H2-receptor antagonists or proton pump inhibitors

Question 14

Chronic Gastritis Treatment?

Answer 14

Parenteral vitamin B12 for type A

triple therapy (bismuth, metronidazole, tetracycline, or amoxicillin for type B