activation of lymphocytes

Question 1

where does the adaptive immune response occur

Answer 1

secondary lymphoid tissues

Question 2

what are secondary lymphoid tissues

Answer 2

sites where T and B cells are activated by antigens, for example lymph nodes, spleen and mucosal lymphoid tissues

Question 3

how to lymph nodes facilitate efficient activation of B and T cells

Answer 3

they are organised into distinct functional areas

Question 4

how do T and B cells enter the lymph nodes

Answer 4

through high endothelial venules (HEV)

Question 5

describe what happens to a B cell when it enters a lymph node

Answer 5

they immediately go into the lymphoid follicle

Question 6

describe what happens to T cells when they enter the lymph node

Answer 6

they stay in T-cell area of the lymph node and interact with dendritic cell that come through the lymph

Question 7

what are B and T cells termed before they are activated

Answer 7

NAIVE B and T cells

Question 8

how do B cells encounter antigens

Answer 8

specialised cells within the B cell zones can ‘trap’ opsonised antigens(which express opsonin receptors)

Question 9

what needs to happens before a B cell becomes fully activated

Answer 9

B cells need to receive 2 signals before they can become fully activated: antigen signals
‘helping’ signals