action potential Flashcards

1
Q

how are neurons named?

A

shape
anatomical features
neurotransmitter
function

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2
Q

what is the input zone of a neuron? (gets info)

A

dendrite

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3
Q

where is the integration zone of a neuron?

A

cell body

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4
Q

where is action potential initiated in a neuron?

A

axon hillock

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5
Q

where does the signal leave the neuron?

A

axon terminal

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6
Q

is an axon long or short?

A

long

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7
Q

what is an action potential?

A

an electrical signal that travels from one end of a cell to the other rapidly

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8
Q

what are the 4 major ions responsible for membrane potential?

A

K
Na
Cl
Ca2

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9
Q

what do electrical signals in neurons depend on?

A

rapid changes in membrane potential

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10
Q

what do ion channels do?

A

mediate the flow of ions that underlie the electrical signals in excitable cells

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11
Q

what is the structure of ion channels?

A

a protein with a water filled pore for ions to go through

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12
Q

what are the properties of ion channels?

A

acts as specific filters
conducting and non-conducting states (open and closed)
gating

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13
Q

why do ion channels gate?

A

changes in membrane potential
ligand binding
mechanical forces

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14
Q

describe step 1 of the action potential of K and Na voltage-gated channels;

A

initial depolarization. caused by trigger. Na channels open

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15
Q

describe step 2 of the action potential of K and Na voltage-gated channels;

A

reaches threshold

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16
Q

describe step 3 of the action potential of K and Na voltage-gated channels;

A

explosive depolarization. Na feed-back loop

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17
Q

describe step 4 of the action potential of K and Na voltage-gated channels;

A

peak potential. Na begins to close and K opens.

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18
Q

describe step 5 of the action potential of K and Na voltage-gated channels;

A

repolarization begins with Na closed and K open

19
Q

describe step 6 of the action potential of K and Na voltage-gated channels;

A

afterhyperpolarization. both cahnnels closed. cannot be restimulated at this stage

20
Q

describe step 7 of the action potential of K and Na voltage-gated channels;

A

resturn to rest ready to be restimulated

21
Q

action potentials are…

A

all or none

22
Q

what type of channel does action potential rely on?

A

voltage gated channels

23
Q

why don’t action potentials wane in size down the axon?

A

they are regenerative

24
Q

what prevents the backward propagation of action potential in the hillock?

A

the refractory period

25
what are the roles of the refraactory period?
prevent backward propagation limit firing frequency
26
what is the absolute refratory period?
no Na channels available so it is impossible to fire an action potential
27
what is the relative refratory period?
more hyperpolarization makes it harder to fire an action potential but not impossible
28
since action potentials are all-or-none, how are differences in the signal intensity conveyed?
firing frequency pattern of action potentials
29
what is saltatory conduction?
what action potential jumps from one node of ranvier to the next
30
what type of cells provide myelin?
glial
31
what is myelin mostly made up of?
cell membrane
32
electrical current propagates faster and farther along a myelinated axon; true or false
true
33
does myelin conduct current?
no
34
is myelin part of the axon?
no
35
do thicker axons conduct faster or slower?
faster
36
spped corresponds with function; true or false
true
37
what is the associated function with A-alpha nerve fibers?
movement sensor, contraction of skeletal muscle
38
what is the associated function with A-beta nerve fibers?
touch
39
what is the associated function with A-gamma nerve fibers?
acute pain
40
what is the role of nodes of ranvier?
propagation and regeneration
40
what factors determine action potential velocity?
axon diameter, myelination and Na channel density
40
what is the associated function with C nerve fibers?
chronic pain, temp and itch
41
what type of cell in the CNS provide myelin?
oligiodendrocytes
42
what type of cells in the PNS provide myelin?
schwann cells