Acquired immunity 2

Question 1

How are microbes involved in the complement cascade?

Answer 1

The pivotal part of the pathway is the conversion of c3 to c3b.

Question 2

Alternative pathway

Answer 2

The c2bBb complex is stabilised by combining microbial polysaccharide, activated and produces a large amount of c3b and c3

Question 3

Classical pathway

Answer 3

Antibodies when bound to a microbe will bind and activate c1q which leads to conversion of c3-c3b

Question 4

Lectin pathway

Answer 4

MBL- Mannose-binding lectin binds mannose and activates a protease that cleaves c4 & c4b2

Question 5

Microbial pathogens for candida albican..

Answer 5

Pattern on cell surface is B-1.3 glucans and that pattern is recognised by Dectin 1.