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Derm Pharm > Acne, Psoriasis > Flashcards

Acne, Psoriasis Flashcards

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Dermatology Board Prep flashcards
1
Q

monitor for depression/suicidal symptoms

A

isotretinoin

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1
Q

p75 TNF receptor

A

etanercept

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2
Q

Increases reactivity to UVR due to MMP inhibition

A

topical retinoids

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3
Q

S/E of corticosteroids?

A

cushing syndrome; dermal atrophy; corticoid rosacea; increased intraocular pressure; acne;

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3
Q

contraindicated in sepsis

A

etanercept

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4
Q

Prodrug

A

benzoyl peroxide (benzoic acid > free radicals)

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5
Q

Mild corticosteroid?

A

hydrocortisone

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6
Q

hypercalcemia => causing abd pain, depression, fatique, weight loss

A

calcipotriene

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7
Q

ustekinumab MOA

A

suppresses formation of pro-inflammatory TH1 and TH17 (via binding of p40 => disruption of IL12/IL23)

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8
Q

musculoskeletal symptoms

A

RAR selective retinoids tretinoin, adapalene, tazarotene

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9
Q

salicylic acid MOA

A

keratolytic + causes desquamation of horny layer of skin

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10
Q

hormonally active form of vit D3

A

calcitriol

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10
Q

binds TNF-alpha

A

adalimumab, etanercept, infliximab

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11
Q

Moderate-strength corticosteroid?

A

betamethasone

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12
Q

treats adult RA only

A

infliximab

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13
Q

contraindicated in heart failure, murine protein sensitivity

A

infliximab

14
Q

Very potent corticosteroid?

A

clobetasol propionate

16
Q

MOA of tretinoin, adapalene, tazarotene

A

bind RAR, affecting cellular diff and prolif

17
Q

increased risk of infection and neoplasm

A

ustekinumab

18
Q

neonatal toxicity via breast milk or contact

A

salicylic acid

19
Q

better tolerated on sensitive skin than calcipotriene

A

calcitriol

19
Q

IV psoriasis medication

A

infliximab

21
Q

vitamin D analog

A

calcipotriene

22
Q

retinoid (related to vitamin A)

A

acitretin

23
Q

Increased penetration in inflamed skin

A

corticosteroids

24
Q

Clinda-erythromycin MOA

A

binds 50S ribosomal subunit

26
Q

epistaxis

A

RAR selective retinoids tretinoin, adapalene, tazarotene

27
Q

Reduced night vision, conjunctivitis

A

RAR selective retinoids tretinoin, adapalene, tazarotene

28
Q

BBW = infection, neoplasia, TB

A

adalimumab, etanercept, infliximab

29
Q

increased susceptibility to UV-induced skin cancer

A

calcipotriene

29
Q

treats Crohns

A

adalimumab, infliximab

31
Q

First line for non-inflammatory acne

A

topical retinoids

32
Q

contraindicated with live virus vaccination

A

ustekinumab

34
Q

IgG1

A

adalimumab, etanercept, infliximab

35
Q

Do not vaccinate concurrently

A

adalimumab, etanercept, infliximab

36
Q

Mucocutaneous symptoms

A

RAR selective retinoids tretinoin, adapalene, tazarotene

Derm Pharm (5 decks)

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