Acid-Base Balance Flashcards
Acid Base Balance
Metabolic processes require a normal range of acid-base balance.
The Balance is reflected by the pH of the blood
Ph is determined by the ratio of acids and bases in the blood
20:1
HCO3- + H2 = H2CO3= CO2 & H20
3 buffer systems
Proteins-albumin, globulins
K+ buffer
Bicarbonate buffer system
- Proteins- albumin, globulins
Change structure to take on or release H+
- K+ Buffer
Exchanges for H+ to reduce acidity
- Bicarbonate Buffer system
Volatile asides- excreted by the lungs
Non volatile acids- excreted by the kidneys
Lungs: Fast and efficient
*Release CO2 in acidotic states and Retain CO2 in alkaline states
Kidney: Slow and efficient
*excretes H+ and regenerates or excretes HCO3- prn
Respiratory acidosis
Excess CO2 level
Ineffective respiration
Low level of consciousness and aren’t breathing well
Respiratory alkalosis
Decreased CO2 level
Excessive respiration
Excitable, breathing in a bag
Metabolic acidosis
Increased levels acid (H+) and/or decreased bicarbonate levels
Excessive metabolic activity or renal failure.
Trauma, disease, physically
Metabolic alkalosis
Decreased H+ levels and/or increased bicarbonate levels
Metabolic loss of acids, and/or gain of alkalinity
Drug overdoses, vomiting.
Normal values
PH: 7.35-7.45
PaCO2: 35-45
HCO3: 22-26
Acidosis
Low ph
Alkalosis
High ph
Respiratory
PaCO2 change
Metabolic
HCO3 change
Respiratory Acidosis cause:
Hypoventilation due to respiratory depression, decreased chest expansion, airway obstruction, decreased alveolar- capillary exchange