Acid-Base Balance Flashcards

1
Q

Acid Base Balance

A

Metabolic processes require a normal range of acid-base balance.
The Balance is reflected by the pH of the blood
Ph is determined by the ratio of acids and bases in the blood
20:1
HCO3- + H2 = H2CO3= CO2 & H20

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2
Q

3 buffer systems

A

Proteins-albumin, globulins
K+ buffer
Bicarbonate buffer system

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3
Q
  1. Proteins- albumin, globulins
A

Change structure to take on or release H+

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4
Q
  1. K+ Buffer
A

Exchanges for H+ to reduce acidity

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5
Q
  1. Bicarbonate Buffer system
A

Volatile asides- excreted by the lungs
Non volatile acids- excreted by the kidneys
Lungs: Fast and efficient
*Release CO2 in acidotic states and Retain CO2 in alkaline states
Kidney: Slow and efficient
*excretes H+ and regenerates or excretes HCO3- prn

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6
Q

Respiratory acidosis

A

Excess CO2 level
Ineffective respiration
Low level of consciousness and aren’t breathing well

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7
Q

Respiratory alkalosis

A

Decreased CO2 level
Excessive respiration
Excitable, breathing in a bag

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8
Q

Metabolic acidosis

A

Increased levels acid (H+) and/or decreased bicarbonate levels
Excessive metabolic activity or renal failure.
Trauma, disease, physically

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9
Q

Metabolic alkalosis

A

Decreased H+ levels and/or increased bicarbonate levels
Metabolic loss of acids, and/or gain of alkalinity
Drug overdoses, vomiting.

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10
Q

Normal values

A

PH: 7.35-7.45
PaCO2: 35-45
HCO3: 22-26

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11
Q

Acidosis

A

Low ph

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12
Q

Alkalosis

A

High ph

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13
Q

Respiratory

A

PaCO2 change

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14
Q

Metabolic

A

HCO3 change

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15
Q

Respiratory Acidosis cause:

A

Hypoventilation due to respiratory depression, decreased chest expansion, airway obstruction, decreased alveolar- capillary exchange

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16
Q

Respiratory Acidosis signs and symptoms:

A

CNS depression, blurred vision, vertigo headache, tachycardia, cardiac dysrhythmias

17
Q

Respiratory Acidosis Compensation:

A

Lungs increase rate and depth of breathing, kidneys eliminate H+ and retain HCO3

18
Q

Respiratory Alkalosis Cause

A

Hyperventilation, fever, anxieties, prolonged sobbing, hypoxemia, salicylate overdose.

19
Q

Respiratory Alkalosis Signs and symptoms:

A

CNS Irritability, lightheaded, parasthesias, cardiac dysrhythmias.

20
Q

Respiratory Alkalosis Compensation:

A

Kidneys hold onto H+ and excrete more HCO3 (slow process) foment not needed

21
Q

Metabolic Acidosis Cause

A

Acid accumulation (DKA, renal failure, starvation, alcoholism, infection, burns, shock) or loss of bicarbonate (diarrhea, vomiting)

22
Q

Metabolic Acidosis Signs and symptoms

A

CNS depression, headache, abdominal pain, cardiac dysrhythmias

23
Q

Metabolic Acidosis Compensation

A

Lungs excrete more CO2 (Kussmaul) kidneys conserve HCO3

24
Q

Metabolic Alkalosis Cause

A

Accumulations of bicarbonate ingesting OTC bicarbonate product, massive transfusion with citrates blood. Loss of Acid: Emesis, gastric suction

25
Q

Metabolic Alkalosis Signs and Symptoms

A

CNS irritability, cardiac dysrhythmias

26
Q

Metabolic Alkalosis Compensation

A

Lungs remain more CO2 (resp depression) kidneys excrete HCO3

27
Q

Compensation

A

Either respiratory or metabolic system becomes abnormal
The opposite system tries to compensate for the abnormality:
* The opposite system moves beyond its normal range to pull the other system back towards normal
Compensation occurs when pH returns to normal