Acid-base balanc Flashcards
1
Q
what can high pH cause?
A
High pH, low H+ can result in alkalosis: -hyperexcitability in sensory neurons and muscles -sustained respiratory muscle contracBon
2
Q
what can low pH cause?
A
Very low pH (excess H+) can result in acidosis: -CNS depression, confusion, coma
3
Q
what is the largest source of acid?
A
CO2 from aerobic metabolism
4
Q
what is a buffer?
A
molecule that moderates, but does not prevent changes in pH by combining with or releasing H
5
Q
ex.s of buffers?
A
bicarb, Hb, phosphate ions (H2PO4, HPO42-)
6
Q
mechanisms of kidney acid-base baance
A
- Directly, by altering the rates of excreBon or reabsorpBon of H+
- Indirectly, by changing the rate at which HCO3- buffer is reabsorbed or excreted
7
Q
what part of the kidney excretes H and reabsorbs HCO3?
A
prox tub
