Acid-Base Flashcards

1
Q

In aqueous solutions H+ usually becomes

A

H3O+

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2
Q

Are H+ ions in greater abundance than other electroyltes in the body?

A

No. There are a lot fewer H+

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3
Q

Are H+ ions highly reactive?

A

YES

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4
Q

Should H+ be kept constant in the body?

A

YES

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5
Q

Do ph and [H+] vary linearly or exponentially?

A

exponentially

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6
Q

the velocity of a reaction is proportional to what?

A

the reactant’s product concentrations

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7
Q

pH equation

A

pH = pKa + log (base/acid)

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8
Q

What is a buffer?

A

a compound that can accept or donate a proton to minimize pH changes

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9
Q

What is in a buffer solution?

A

weak acid, and its conjugate base

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10
Q

What is the first line of defense to prevent major changes in pH in the blood?

A

Blood buffers

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11
Q

What is isohydric principle?

A

multiple buffers in solution are in equilibrium. so if you know one system you can predict the changes in the other systems

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12
Q

ionic composition of bodily fluids are maintained within NARROW limits: true or false

A

true. a small change in pH can have drastic effects

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13
Q

What 3 systems help regulate pH and H+ in bodily fluids?

A

1) Chemical buffers (manage imbalance)
2) Lungs
3) Kidneys

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14
Q

How do the kidneys and lungs help regulate pH?

A

they try to correct pH by changing ventilation or renal function

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15
Q

pH equation with lungs and kidneys

A

pH = pKa + log (renal function/ventilation)

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16
Q

First line of defense?

A

Buffers!

17
Q

3 types of buffers?

A

1) Proteins (Hemoglobin, plasma proteins)
2) Bicarbonate buffer system
3) Phosphate buffer system

18
Q

what are one of the most plentiful buffers?

A

proteins

19
Q

Where are most proteins located?

A

Intracellularly

20
Q

What intracellular buffer works fastest on the ECF acid base problems?

A

Hemoglobin (Red Blood Cells)

21
Q

What are the most important blood buffers?

A

Hemoglobin and bicarbonate buffer system

22
Q

Does hemoglobin have a large or small number of acid-base groups?

A

Large number

23
Q

2 ways hemoglobin buffers?

A

1) adds hydrogen to carboxyl group (takes out of solution)
2) Imidazole groups of histidine
- H+ binds to iron of heme group