Accessory glands Flashcards
What are glands?
Organised clusters of secretory units
What do glands arise from?
Invaginated epithelial cells
Describe the increasing complexity of a digestive gland (ducts deeper into the gland)
Main duct
Lobar duct
Interlobar duct
Intralobular duct
Striated duct
Intercalated duct
Acinus
What cells line the lobar duct?
Stratified columnar epithelia
What cells line the interlobar duct?
Pseudostratified columnar epithelium
What cells line the intralobar duct?
Cuboidal to columnar epithelia
What cells line the striated duct?
Cuboidal to columnar epithelia
What cells line the intercalated duct?
Low cuboidal epithelium
What is an acinus?
Rounded secretory units
What does saliva contain?
Proteins, glycoproteins (mucus), ions, water and IgA.
What are the two portions of the salivary gland?
Secretory portion
Duct portion
What cell types make up the secretory portion of the salivary gland?
Serous cells
Mucous cells
Myoepithelial (basket) cells
What is a characteristic feature of the myoepithelial basket cells?
Have several long processes that envelope the acinus
What is characteristic about the duct portion of the salivary glands?
Highly branched levels
What are the 3 major salivary glands?
Parotid
Submandibular
Sublingual glands
What is mainly secreted from the parotid?
Serous secretion with high levels of the enzyme amylase
What salivary gland produces most of the saliva?
Submandibular
What do minor salivary glands mainly secrete?
Mucous
Talk about how enzymes are stored in pancreas and salivary cells?
Stored as zymogens in acinar cells - released by exocytosis
Describe what system innervates salivary glands
Post ganglionic fibres of autonomic nervous system
How are salivary and pancreatic ducts similar
Both have branching ductal system which epithelial cells secrete into
Both compromise secretory units (lobules) made of an acinus - intercalated duct - intralobular duct - interlobular duct - pancreatic/salivary duct
Both store zymogen granules in acinar cells
Desribe difference histologically between endocrine and exocrine pancreas
Exocrine pancreatic acinus release enzymes into duct
Endocrine pancreas cells release hormones into capillaries (capillaries in middle of islets)
What do centroacinar cells do?
Pancreas - Form intercalated ducts and secrete buffer solution