ABG interpretations Flashcards
Shift to the left
Increasing Hbg affinity for oxygen
Shift to the right
Decreasing Hgb affinity for oxygen
Carboxyhemoglobin
- hgb has as 200-250x greater affinity for CO2 than O2
- Shift to the left
- cherry red lips
Methomeglobin
- Oxidized hgb molecules
- shift to the left
- reddish brown blood, cyanosis (blue people)
Management: methylene blue
Fetal hemolgobin
- Two beta chains are absent and two gamma chains are present
- Shift to the left
- Spontaneous resolution
Hypoxemia Hypoxia
- pO2 supply is deficient
- ex. pneumothorax, high altitudes
Anemic Hypoxia
- Decreased oxygen carrying capacity deficient hbg
- decreased hbg = anemia
- decreased ability to bind = carboxyhemoglobin and methemoglobinemia
Circulatory Hypoxia
- Stagnant (cardiogenic)
- arterial-venous shunting ( septic shock)
Histotoxic Hypoxia
- Inability of the tissue to use oxygen, cell death
- cyanide poisoning - sodium nitroprusside toxicity
pH
< 7.35 = acidosis
>7.45 = alkalosis
pCO2
<35 = low >45 = high
HCO3
<22 = low >26 = high
R.O.M.E
- Respiratory (PCO2) = opposite direction than pH
- Metabolic (HCO3) = equal/same direction to pH
Respiratory acidosis
Chlorine inhalation injury, asthma, pneumonia
Respiratory alkalosis
Hyperventilation, anxiety
Metabolic acidosis
Acid gain, anion gap-shift in electrolytes (Na+, Cl-, HCO3-)
MUD PILE CATS
M: menthol, metformin U: Uremia D: DKA P: paraldehyde, pregnancy I: isoniazid and iron L: lactic acidosis E: ethylene glycol C: carbamazepine A: alcoholic ketoacidosis T: Theophylline S: salicylates, starvation ketoacidosis
Metabolic Alkalosis
Acid loss, Bicarb gain, tx: saline responsiveness