ABDOMEN + ELECTROLYTES & pH W5 Flashcards
Name the 6 general functions of the GI-Tract
- Ingestion
- Mechanical digestion
- Chemical digestion
- Secretion
- Absorption
- Defecation
Functions of the oral cavity
- Crushes/sheares food = mechanical digestion
- Lubricates food
- Begins chemical digestion
- Senses and analyses food
Functions of the tongue
- Prepares food for swallowing
- Produces lingual lipase
- Rich in sensory cells (sweet, sour, salty, bitter, savoury)
- Important for speech
Pathophysiology in the oral cavity in relation to bacteria
- Bacteria colonises oral cavity
- Bacteria breaks down sugar and releases acid and builds up plague damaging the emal
Salivary glands produces
Saliva
What is the functions of saliva
- Moists the food
- Contains enzyme
- Provides antibodies (IgA) and lysosome for protection of the mouth
What are the 3 regions of the throat?
- Nasopharynx
- Oropharynx
- Laryngopharynx
What leads the food “bolus” from the pharynx to the stomach?
Oesophagus
The 3 phases of swallowing?
- Buccal phase
- Pharyngeal phase
- Oesophageal phase
What are the functions of the stomach
- Storage of ingested food
- Mechanical and chemical digestion
- Production of acid/enzymes
- Production of intrinsic factor (for B12 absorption)
What is the function of the lower Oesophageal Sphincter?
Contracts to keep the ingested food in the Fundus of the stomach
Name the 3 cells of the stomach and their function
- Parietal cells (produces hydrochloric acid)
- Chief cells (produces pepsinogen)
- Mucous cells (protects mucosa)
What is GERD?
Incompetence of LES
Causing acid to harm the oesophagus resulting in inflammation and burning chest pain.
What is the treatment of GERD?
PPI (proton-pump-inhibitors) that affects the parietal cells causing less production of acid.
Name a common PPI drug
Pantropazole
What is gastritis?
Inflammation of the stomach due to imbalance of acids and protective components
Name the 3 structures of the small intestines
- Duodenum
- Jejunum
- Ileum
What is the function of the small intestines?
90% of chemical digestion and nutrient absorption happens here
What is the function and characteristics of duodenum?
- C-Shaped first segment approx. 25cm long
- “Mixing bowl” of chyme, bile and pancreatic juice
- Has few folds and small vilii
- Absorbs the majority of iron in chyme
What is the function and characteristics of jejunum?
- 2m long
- Many folds and vili (increasing surface)
- Responsible for the bulk of chemical digestion and nutrient absorption
What is the functions and characteristics of Ileum?
- 3m long
- Quite similar to Jejunum (but har smaller vili)
- Has lymphatic nodes at the terminal end that protects the small intestine from bacteria from the colon.
- Absorbs Vitamin B12
Name the 3 segments of the large intestine
- Cecum
- Colon
- Rectum
Name the 3 segments of the colon
- Ascending
- Transverse
- Descending
What is the function of the large intestine?
- Compacting intestinal content into faces
- Absorbing bile-salts and vitamines
- Storage of feces
Where is the appendix attached?
To the Cecum
What is the function of cecum?
- Receives intestinal juice from ilocecal valve
- Reabsorbes water and sodium
3.Origin of the appendix
Symptoms of appendicitis
- Pain migrating from the umbilicus to the RLQ above the appendix
- Nausea/vomiting
- Diarrea
- Elevated WBC levels
- Fever
How long does it normally take from infection of the appendix before it ruptures?
48-72 hours
What is the function of the colon?
Compacts faces and reabsorbs water and sodium
What is the function and characteristics of the rectum?
- 15cm long
- Stores feces
- Rectal distention causes urge to defecate
- Some of the veins drains directly into the vena cava and some into hepatic portal
Food requirements
25kcal/kg per day
50-55% carbohydrates
25-30% lipids
15-20% proteins
Water requirements
30ml/kg per day
What is the difference in energy deprived from lipids vs proteins and carbohydrates?
1g lipid=9kcal
1g carb or protein=4kcal
What is the contents of stool?
- Water (75%)
- Indigestible materials (20%)
- Bacteria (5%)
What is the average normal defecation frequency?
Anything between once every 3 days up to 3 times a day
Causes of constipation?
- Age/gender
- Immobile lifestyle
- Low fibre diet
- Low liquid intake
- Hypothyrodism (slow metabolism)
- Opiod intake
- Fear of bathrooms
Treatment of constipation
- Address underlying disease
- Increase fibre and liquid intake
- Increase physical activity
- Use laxatives (movicol, dulcolax)
Causes of diarrea
Infections (viral/bacterial/paracites)
RED flag symptoms of dysentery (infection of intestines)
- Crampy abdominal pain
- Bloody diarrea
- Fever >38,5
Treatment of diarrea
- Rehydrate (oral or IV)
- Isolate patient
- Medicine (loperamid)
- Abx if indicated
3 most important functions of the lever
- Metabolic regulation
- Hematologic regulation
- Bile production
General functions and characteristics of the liver
- Largest visceral organ (1,5kg)
- Center of metabolism
- Capability to regenerate
- Absorbed nutrients and drugs enter the lever via the hepatic portal system
What is the function of metabolic regulation in the liver?
- Venous blood from the portal veins drains into the liver
- Mobilizes reserves and synthesizes nutrients
- Removes or decomposes metabolic waste
What happens in the liver during events of low BS (blood sugar)?
Glycogen gets transformed into glucose that is released into the blood to raise BS-level
What happens in the liver during events of high BS (blood sugar)?
Glucose in the blood gets transformed into glycogen or fat and is stored.
What is the function of hematologic regulation?
- Production of plasma proteins
- Macrophages in the liver removes aged/damaged blood cells.
- Macrophages removes pathogens and act as antigen-presenting cells to activate the immune system
What is bile?
An alcaline liquid consisting of water and bile-salts produced by the liver
What gives bile its colour?
Hemoglobine of the old/damaged RBC’s decomposes to bilirubin in the liver. Bilirubin ads a yellowish/green colour to the bile
What is the function of bile?
- Counterweights the hydrochloric acid of the stomach
- Emulsifies lipids so that enzymes in the GI-tract can digest them
What is the function of the gallbladder?
- Stores bile between meals
- Concentrates bile
What can cause jaundice?
- Increased production of bilirubin (e.g. in malaria)
- Lever dysfunction (infection, toxins, cirrhosis)
What are the causes and symptoms of Hepatitis
Causes: Inflammaition of the liver due to alcohol, medications or infection.
Symptoms: Fatigue, fever, nausea, jaundice, pain.
What is the characteristics of Hepatitis A?
- Tramsmission via fecal/oral route
- Causing acute hepatitis
- Prevention with vaccine.
- Symptomatic treatment
What are the characteristics of Hepatitis B?
- Transmission via sex, blood products or mother to newborn
- Causing acute hepatitis
- Prevention with vaccine.
- Treatment is difficult
What are the characteristics of Hepatitis C?
- Transmission via blood products or surgical equipment
- Causing mainly chronification
- Not preventable with vaccine
- Treatable
What is cirrhosis?
- End stage liver disease
- Transformation of liver tissue into fibrous tissue
What is gallstone disease caused by?
Imbalance of substances in bile causing “crystals” to build.
Typically caused by high cholesterol levels in blood