A&P Exam 1 (Chap 1-8) Flashcards
Polymer
a long/large molecule consisting of many similar building blocks/units (ie monomers)
Examples of polymers
- Carbohydrates
- Proteins
- Nucleic acids
Carbohydrates
simple sugars and polymers of sugars
Simplest Carbohydrates
Monosaccharides
Function of polysaccharides
energy storage (ie glycogen)
Glycogen storage
stored in liver and muscle cell
Hydrolysis of glycogen
Releases glucose when the demand for energy increases
Lipids
do not form polymers, are hydrophobic & nonpolar
Saturated fatty acids
solid at room temperature
Unsaturated fatty acids
liquid at room temperature
Most biologically important lipids
fats, phospholipids, & steriods
Functions of fats
energy storage (better at energy storage than carbo & protein)
Adipose cells
contains long-term energy reserves
Adipose tissue
cushions vital organs & insulates the body
Proteins
work as enzymes, function in defense, storage, transport, cellular communication, movement, and structural support. (made from the same set of 20 amino acids)
Polypeptides
unbranched polymers built from amino acids
Polypeptides
unbranched polymers built from amino acids
Protein diversity
- Enzymatic proteins
- Defensive proteins
- Storage proteins
- Transport proteins
- Hormonal proteins
- Receptor proteins
- Contracile and motor proteins
- Structural proteins
Enzymatic proteins
Func: selective acceleration of chemical rxn
Ex: Digestive enzymes
Defensive proteins
Func: Protection against disease
Ex: Antibodies inactivate and help destroy viruses and bacteria
Storage proteins
Func: Storage of amino acids
Ex: Ovalbumin
Transport proteins
Func: Transport of substances
Ex: Hemoglobin
Hormonal proteins
Func: Coordination of an organism’s activities
Ex: Insulin
Receptor proteins
Func: Response of cell to chemical stimuli
Ex: Receptors built into the membrane of a nerve cell
Contractile and motor proteins
Func: Movement
Ex: Motor proteins
Structural proteins
Func: Support
Ex: Keratins
Nucleic Acids Functions
Store, Transmit, and Help express hereditary informations
Nucleotides Composition
nitrogenous base, pentose sugar, and one or more phosphate group
Somatic cells
all body cells except sex cells
Centrosomes and Centroles
Func: essential for movement of chromosomes during cell division; organization of microtubules in cytoskeleton (needed for cell reproduction)
Cytoskeleton
Func: strength and support; movement of cellular structures and material
Composition: Protein organized in fine filaments or slender tubes
Plasma Membrane
Func: Isolation; protection; sensitivity; support; controls entry and exit of material
Composition: lipid bilayer containing phospholipids, steroids, and carbohydrates
Microvilli
Func: increases surface area to facilitate absorption of extracellular materials( expands surface area to gain more nutrients)
Cilia
Func: acts as a sensor. Motile cilia move materials over cell surfaces
Ex: in airway & lungs to wipe away mucous
Composition: long extensions of the plasma membrane containing microtubules. 2 types: primary and motile
Proteasomes
Func: Breakdown and recycling of damaged or abnormal intracellular proteins (garbage disposal of damaged or broken protein)
Composition: Hollow cylinders of proteolytic enzymes with regulatory proteins at their ends
Ribosomes
Func: Protein synthesis
Composition: RNA+protiens; fixed ribosomes bound to rough endoplasmic reticulum; free ribosomes scattered in cytoplasm
Golgi apparatus
Func: Storage, alteration, and packaging of secretory products and lysosomal enzyme
Mitocondrial
Func: Produce 95% of the ATP required by the cell
Endoplasmic reticulum (ER)
Func: Synthesis of secretory products; intracellular storage and transport; detoxification of drugs or toxin
Composition: Rough ER has ribosomes
Smooth ER does not have ribosomes
Peroxisomes
Func: Catabolism of fats and other organic compounds; neutralization of toxic compounds generated in the process (breaks down toxic compounds)
Lysosomes
Func: Intracellular removal of damaged organelles or pathogens (degrade everything)
Nucleus
Func: Control of metabolism storage and processing of genetic information; control of protein synthesis
Tissue
refers to certain collections of specialized cells and cell products that perform specific functions
4 types of tissue
- Epithelial
- Connective
- Muscle
- Nervous
Epithelial Tissue
- Covers exposed surfaces
- Lines internal passageways and chambers
- Produces glandular secretions
Connective Tissue
- Fills internal spaces
- Provides structural support
- Store energy
Muscle Tissue
- Contracts to produce movement
Nervous Tissue
- Propagates electrical impulses
- Carries information
Composition of Epithelial Tissue
- Epithelia
- Glands
Epithelia
layers of cells covering internal or external structure
Glands
Structures that are attached to or derived from epithelia produce fluid secretions
Functions of epithelial tissue
- Provide physical protection
- Control permeability
- Provide sensation
- Produce specialized secretions
Characteristics of Epithelial Tissue
- Polarity (apical and basal/lateral surfaces)
- Cellularity (cell junctions)
- Attachment (basement membrane)
- Avascularity (avascular)
- Regeneration
Cell junction
- Gap Junction
- Tight Junction
- Desmosome
Gap Junction
- Formed by interlocking transmembrane proteins (connexons) –> narrow passages
- Allow small molecules and ions to pass –> rapid communication
- Coordination contractions in heart muscle and smooth muscle
Tight Junction
- Fusion of the cell membranes
- Prevents the diffusion of fluids/solutes between cells
Desmosome
- Hemidesmosome
- Spot desmosome
Classification of epithelia
Based on shape:
1. Squamous- thin & flat
2. Cubodial- squared shaped
3. Columnar- tall, slender rectangles
Based on layers
1. Simple epithelium- single layer of cells
2. Stratified epithelium- several layers of cells
Simple Squamous Epithelium
Func: Reduces frictions; controls vessel permeability; performs absorption and secretion
Ex: Mesothelia lining pleural, alveoli of lungs
Stratified Squamous Epithelium
Func: Provides physical protection against abrasion, pathogens, and chemical attack
Ex: Surface of skin; lining of mouth, throat, esophagus
Simple Cuboidal Epithelium
Func: Limited protection, secretion, absorption
Ex: Glands; ducts; thyroid gland
Transitional (Stratified Cuboidal) Epithelium
Func: Permits repeated cycles of stretching without damage
Ex: Urinary bladder, renal pelvis, ureters
Simple Columnar Epithelium
Func: Protection, secretion, absorption
Ex: Lining of stomach, intestine, gallbladder, uterine tubes, and collecting ducts of kidney
Pseudostratified Ciliated Columnar Epithelium
Func: Protection, secretion, move mucus with cilia
Ex: Lining of nasal cavity, trachea, & bronchi
Glandular epithelia
- Endocrine glands
- Exocrine glands
Endocrine glands
Release hormones into bloodstream, No ducts
Exocrine glands
Produce exocrine secretions, Discharge secretions through ducts onto epithelial surfaces
Exocrine glands Types
- Unicellular
- Multicellular
Goblet cells
are unicellular glands in epithelia of intestines and respiratory tract, secrete mucin, which mixes with water to form mucus
Multicellular exocrine glands
- Structure of the ducts
- Simple (undivided)
- Compound (divided) - Shape of secretory portion of the gland
- Tubular (tube shaped)
- Alveolar or acinar (sack shaped/blind pockets)
Types of secretions
- Merocrine secretion
- Apocrine secretion
- Holocrine secretion
Merocrine secretion
Released by secretory vesicle (exocytosis)
ex: sweat & salivary glands
Apocrine secretion
Released by shedding cytoplasm
ex: mammary glands
Hoolocrine secretion
Released by cell bursting, Gland cells are replaced by stem cells
Ex: sebaceous glands
Connective Tissue
- a type of tissue with a diverse array of cells and other components
- closely associated with epithelial tissue- connecting it to the rest of the body
- Never exposed to the outside environment
- Highly vascular
- Contain sensory receptors
Categories of Connective
- Connective tissue proper
- Fluid connective tissues
- Supportive connective tissues
Connective tissue proper
Connect and protect
Cells: Fibroblasts, Fibrocytes, Adipocytes, Mesenchymal cells, Melanocytes, Macrophages, Mast cells, Lymphocytes, Microphages
Protein fibers: Collagen fibers, Reticular fibers, Elastic fibers
Ground substance: …
Tissue Membrane
Line or cover body surface, physical barriers
Consist of an epithelium supported by connective tissue
Types of tissue membrane
- Mucous membrane (Mucosa)
- Serous membranes (Serosa)
- Cutaneous membrane
- Synovial membranes
Mucous Membrane
Line passageways including digestive, respiratory, urinary, and reproductive tracts
Func: to reduce friction, to facilitate absorption or secretion
Serous membrane aka Serosa
Line internal cavities of the body that do not open to the outside
- Parietal layer lines inner surface of cavity
- Viseral layer covers the organs
- Serous fluid between the 2 layers reduce friction
Pleura
lines pleural cavities, covers lungs
Pericardium
lines pericardial cavity, cover heart
Peritoneum
lines peritoneal cavity, covers abdominal organs
Cutaneous Membrane
Skin that covers the outer surface of the body; Thick, relatively waterproof, and usually dry
Synovial Membrane
Line synovial joint cavities; synovial fluid produced for lubrication, lack a true epithelium