A&P 2.8 - The Cardiovascular System Flashcards
Blood - Characteristics
- Type of tissue
- Temperature
- Volume in the body
- Average weight
- Connective tissue
- 100.4 degrees
- Males: 5-6 liters, Females: 4-5 liters
- Blood makes 8% of body weight
Blood
List the functions of blood
- Distribution
- Regulation
- Protection
Blood - Functions
Describe distribution
Transports O2, nutrients, hormones and waste products throughout the body
Blood - Functions
Describe regulation
Helps maintain homeostasis by regulating temperature, pH, and water balance (how much and where in the body)
Blood - Functions
Describe protection
Serves in immune defense against pathogens and aids clotting to prevent excessive bleeding
Blood
Composition
- Plasma
- Formed Elements
**RBC
**WBC
**Platelets
Blood - Composition
Plasma
- 55% of whole blood
- 90% water
- viscous, thick fluid
- straw-colored from formed elements
Blood - Composition
Formed elements
- 45% of whole blood
- not always true cells
Blood - Composition - Formed Elements
Red blood cells
- Cells that transport O2 and CO2 in blood
- Contain hemoglobin for gas exchange
- Grow and mature in the bone marrow
“Erythrocytes”
Blood - Composition - Formed Elements
White blood cells
- True cells involved in immune system that defend the body against infections and foreign substances
- Grow and mature in bone marrow and play a crucial role in the body’s defense mechanisms (phagocytosis)
“Leukocytes”
Blood - Composition - Formed Elements
Platelets
- Half-moon shaped structures formed from by-products of RBC formation
- They have a curve shape to accumulate around broken blood vessel walls
“Thrombocytes”
Hemostasis
Definition
The mechanism by which the bleeding of a blood vessel ceases
Hemostasis
List the phases
- Vascular spasm
- Platelet plug formation
- Coagulation/blood clotting
Hemostasis - Phases
Vascular spasm
immediate narrowing of blood vessels o reduce blood flow to affected area => minimizing blood loss
Hemostasis - Phases
Platelet plug formation
Platelets adhere to site of injury forming a temporary “platelet plug” to seal small breaks in blood vessels
Hemostasis - Phases
Coagulation/blood clotting
- Clotting factors activate formation of a stable blood clot reinforcing the platelet plug
- This phase involves a complex series of biochemical reactions
The heart
- Size
- Weight
- Location
- Pericardium
- Heart wall
- About the size of a fist
- Weighs less than 1#
- Located within the mediastinum - the medial cavity of the thorax between the lungs.
**Sits on the diaphragm - Pericardium
**Fibrous
**Serous - Heart wall
**Epicardium
**Myocardium
**Endocardium
The Heart
Pericardium definition and function
- Double-layered sac surrounding the heart
- Provides protection and anchors the heart in the chest
The heart - Pericardium
Fibrous pericardium
- Tough outer layer of pericardium that provides structural support and prevents overstretching of the heart
The heart - pericardium
Serous pericardium
- Inner, thinner layer of pericardium
- Consists of parietal & visceral layers
- Produces pericardial fluid which reduces friction between the layers of the heart during contraction
The heart wall
List the layers
- Epicardium
- Myocardium
- Endocardium
The Heart Wall
Epicardium
Outer layer of heart wall which provides protection
Also known as the visceral layer of serous pericardium
The Heart Wall
Myocardium
Middle layer of heart wall consisting of muscle tissue for pumping blood
The Heart Wall
Endocardium
- inner layer lining the chambers and valves
- facilitates smooth blood flow
Anatomy of the Heart
Chambers
- Atria
- Ventricles
Anatomy of The Heart
List the major components of the heart
- Chambers
- Valves
- Major Vessels
- Interventricular septum
Anatomy of the Heart - Chambers
Atria
- Receive blood
– Right: receives deoxygenated blood from all areas
– Left: receives oxygenated blood from the lungs
Anatomy of the Heart - Chambers
Ventricles
- Expel blood
– Right: expels deoxygenated blood into the pulmonary trunk
– Left: expels oxygenated blood into the aorta
Anatomy of the Heart
List the two major valve types
- Atrioventricular
- Semilunar
Anatomy of the Heart - Valves
Atrioventricular
(2)
- Tricuspid
- Bicuspid
Anatomy of the Heart - Valves - Atrioventricular
Tricuspid
- Between the R atrium and R ventricle
- Has 3 anchors
Anatomy of the Heart - Valves - Atrioventricular
Bicuspid
- Between the L atrium and L ventricle
- Has 2 anchors
“mitral valve”
Anatomy of the Heart - Valves
Semilunar (2)
- Pulmonary semilunar
- Aortic semilunar
Anatomy of the Heart - Valves - Semilunar
Pulmonary semilunar
Between R ventricle and pulmonary trunk
Anatomy of the Heart - Valves - Semilunar
Aortic semilunar
Between L ventricle and aorta
Anatomy of the Heart - Major Vessels
List the major vessels of the heart
- Pulmonary trunk
- Pulmonary veins
- Pulmonary arteries
- Aorta
- Superior vena cava
- Inferior vena cava
Anatomy of the Heart - Major Vessels
Pulmonary trunk
Carries deoxygenated blood from R ventricle to pulmonary arteries
Anatomy of the Heart - Major Vessels
Pulmonary arteries
Carry deoxygenated blood to lungs
Anatomy of the Heart - Major Vessels
Pulmonary veins
Carry oxygenated blood from lungs to L atrium
Anatomy of the Heart - Major Vessels
Aorta
- Largest artery in the body
- Carries blood to every cell
Anatomy of the Heart - Major Vessels
Superior vena cava
Delivers deoxygenated blood from all areas of the body above the diaphragm into the R atrium
Anatomy of the Heart - Major Vessels
Inferior vena cava
delivers deoxygenated blood from all areas of the body below the diaphragm to the R atrium
Anatomy of the Heart
Interventricular septum
wall between ventricles that serves as a pathway for nerve signals called action potentials
The Heart
Circulatory pathways (3)
- Coronary
- Systemic
- Pulmonary
The Heart - Circulatory Pathways
Coronary
- The heart’s own pathway
- Small holes in aorta open during relaxation of heart to allow blood to diffuse into vessels
The Heart - Circulatory Pathways
Systemic
From aorta to every cell in the body
The Heart - Circulatory Pathways
Pulmonary
From heart to lungs to heart
Pathway of Blood Flow Through Heart
List basic flow starting with R atrium
De-O2 blood enters R atrium -> tricuspid valve -> R ventricle -> pulmonary semilunar valve -> pulmonary trunk -> pulmonary arteries -> lungs (CO2/O2 exchange) -> pulmonary veins -> L atrium -> bicuspid (mitral) valve -> L ventricle -> aortic semilunar valve -> aorta -> O2 brought to every cell in body & exchanged with CO2 waste) -> de-O2 blood returns to R atrium via superior/inferior vena cava
Cardiac Pathologies
Angina Pectoralis
chest pain due to reduced blood flow to heart
“ pain chest”
Cardiac Pathologies
Incompetent valves
heart valves that don’t close properly causing backward blood flow
Cardiac Pathologies
Myocardial infarction
results from bloked blood flow to part of the heart muscle (myocardium)
“heart attack”
The Intrinsic Conduction System
List the two components of this system
- Autorhythmic (excitable) cells
- Gap junctions
The Intrinsic Conduction System
Autorhythmic cells
heart cells with inherent pacemaker activity that can spontaneously depolarize
The Intrinsic Conduction System
Gap junctions
- channels allowing direct electrical communication between adjacent cells in heart
- one stimulus resulting in 2 contractions
The Intrinsic Conduction System
Sinoatrial (SA) node
- heart’s natural pacemaker
- initiates electrical impulses that regulate the heart’s beating
- located in R atrium
The Intrinsic Conduction System
Atrioventricular (AV) node
- cluster of cells in the heart that slows down electrical impulses
- allows atria to contract before ventricles to coordinate the heart’s rhythmic pumping
The Intrinsic Conduction System
Atrioventricular bundle
specialized fibers transmitting electrical impulses from AV node to ventricles for synchronized heart contraction
The Intrinsic Conduction System
Bundle branches
carry eelctrical signals down L and R sides of heart’s septum to aid in coordinated ventricular contraction
The Intrinsic Conduction System
Purkinje fibers
specialized cardiac muscle fibers that spread electrical impulses throughout ventricles
Cardiac Vocabulary
Tachycardia
- abnormally fast HR
- 100+ bpm
- A-fib = chaotic beating
The Intrinsic Conduction System
Bradycardia
- abnormally slow HR
- 60bpm or less
- can be normal with conditioned athletes
The Cardiac Cycle
Definition and duration
- All mechanical events associated with 1 complete heartbeat
- ~0.8 seconds
The Cardiac Cycle
Systole
- contraction phase
- Atrial = 0.1sec
- Ventricular = 0.3 sec
The Cardiac Cycle
Diastole
- relaxation phase
- 0.4 sec
Heart Sounds
List the different sounds (3)
Auscultation
- lubb (AV valves closing)
- dubb/dupp (semilunar valves closing)
- pause
The Heart
Cardiac Output: definition and formula
- Amout of blood expelled by ventricles per minute
- stroke volume x BPM
Cardiac Output
Stroke volume: definition & average volume
- amount of blood expelled by ventricles per contraction
- 70mL (2oz) blood
Cardiac Output
Average HR Healthy Adult (calculation based on avg BPM)
70mL (2oz) x 75bpm => 5250mL =5.25L blood/minute
Cardiac Output - Regulation of Stroke Volume
Starling’s Law of the Heart
increased venous return = increased cardiac output
decreased venous return = decreased cardiac output
Cardiac Output - Regulation of Stroke Volume
How does exercise affect this?
increases venous return
Cardiac Output - Regulation of HR
List the 3 categories/methods of HR regulation
- Autonomic nervous system (ANS)
- Chemical
- Physical factors
Cardiac Output - Regulation of HR
Describe how the ANS impacts HR
- Sympathetic state = increased HR
- Parasympathetic state = decreased HR
Cardiac Output - Regulation of HR
Describe what chemicals may effect this and how so
- Thyroxin: hormone that controls metabolic function = increased HR
- Adrenaline/Epinephrine = increased HR
Cardiac Output - Regulation of HR
What physical factors affect HR? (4)
- Temperature
- Sex
- Age
- Exercise
Cardiac Output - Regulation of HR - Physical Factors
Describe temperature’s affect on this
- Heat = increased HR
- Cold = decreased HR
Cardiac Output - Regulation of HR - Physical Factors
Describe how sex affects this
Sex @ birth:
- Male = 64-72bpm
- Female = 72-80bpm
Cardiac Output - Regulation of HR - Physical Factors
Describe how age affects this
fetal HR = 140-160bpm
Cardiac Output - Regulation of HR - Physical Factors
Describe how exercise affects this
- increases HR temporarily
- continuous conditioning can lower resting HR over time by improving output and efficiency
Blood Vessels
List the structures that compose a blood vessel wall
- Tunica intima
- Tunica media
- Tunica externa
- Lumen
- Valves
Blood Vessel - Structures of the wall
Tunica intima
- Innermost layer of vessel
- Composed of epithelial cells for smooth blood flow
- In direct contact w/ blood
Blood Vessel - Structures of the wall
Tunica media
- Intermediate layer
- Composed of smooth muscle and elastic fibers
- Regulates vessel diameter
Blood Vessel - Structures of the wall
Tunica externa
- Outer layer
- Made of CT
- Provides support for blood vessels
Blood Vessel - Structures of the wall
Lumen
Central, hollow portion of blood vessel where blood flows
Blood Vessel - Structures of the wall
Valves
- Flap-like structures in veins
- Prevent backward blood flow and ensures one-way circulation
Blood Vessels - Arteries
Characteristics
- Carry blood away from heart
- Most carry O2 blood
- Mostly deep
- No valves
- Higher BP than veins due to proximity to heart
- Ticker tunica media layer
Blood Vessels - Arteries
Types
- Elastic
- Muscular
- Arterioles
Blood Vessels - Artery Types
Elastic
- Closest to heart
- More elastic fibers to resist BP
Blood Vessels - Artery Types
Muscular
Serve the major organs
Blood Vessels - Artery Types
Arterioles
- Smallest type
- Can re-route blood to a different area if needed (i.e. injury)
Blood Vessels - Arteries
Capillaries
- smallest of artery vessels
- serve every cell of the body
- Only have tunica intima
- some are only one cell layer thick (allowing for gas exchange)
Blood Vessels - Veins
Characteristics
- Carry blood to the heart
- Have valves
- Most carry de-O2 blood
- can be a blood reservoir (back of calves, blood pools here)
- superficial + deep
- less tunia medica and more tunica externa (increase in support to help fight gravity)
Blood Vessels - Veins
Types
Venules
Blood Vessels - Vein Type
Venules
- smallest veins
- capillaries merge into them to carry CO2 away
Blood Vessels - Veins
Venous return is aided by…? (3)
- skeletal muscle pump
- respiratory pump
- swedish massage
Blood Vessels - Veins
Describe how skeletal muscle pumps aid venous return
- contraction and relaxation of skeletal muscle aids blood flow towards the heart
- particularly helpful in extremities
Blood Vessels - Veins
Describe how the respiratory pump aids in venous return
- changes in thoracic pressure during breathing assist blood flow back to the heart due to diaphragm movement
- diaphragm depressin during exhale compresses the abomdinal cavity and increases pressure
Blood Vessels - Veins
Swedish massage
Theorhetically increases venous return during centripetal, effleurage strokes
Blood Vessels - Vein Vocabulary
Thrombus
blood clot that forms inside a blood vessel causing a blockage while still attached to b.v. wall
Blood Vessels - Vein Vocabulary
Embolus
- A detached clot or material that travels through the blood stream
- capable of causing a blockage at a distant site within the body
Blood Vessels - Vein Vocabulary
Varicosity
- abnormal dilation of veins
- marked by twisted, swollen vesssels due to weakened valves and impaired blood flow
Arterial Pulse
- Physical palpation of expansion and recoil of superficial arteries
- Often sites used: Radial wrist (radial artery) & carotid (more popular in eastern medicine)
Define blood pressure
- Force exerted inside of blood vessels by contraction
- Average should be ~120/80bpm
Blood Pressure
How to measure - 2 parts
- Systolic
- Diastolic
Blood Pressure
Define systolic
contraction of ventricles
Blood Pressure
Define diastolic
relaxation of ventricles
Blood Pressure
List the factors that effect BP
- condition of blood vessel walls (firmer walls need more force)
- ANS
- Renal factors (enzyme renin prodcued by kidneys to control water balance of blood in order to maintain proper viscosity)
- Temperature: cold = increased BP, hot = decreased blood pressure
- Hormones: Thyroxine & epinephrine increase BP
- Diet: out of scope for MTs