9.2-DNA VIRUSES Flashcards
The smallest DNA viruses with a particle size of 18–26 nm
Parvoviruses
The symmetry of parvoviruses, consisting of 32 capsomeres
Cubic symmetry
The presence or absence of an envelope in parvoviruses
None (naked virus)
The genome structure of parvoviruses
Linear, single-stranded DNA
The site where parvoviruses replicate and assemble their capsid
Nucleus
A defective parvovirus that requires adenovirus for replication
Adeno-associated satellite virus
The human parvovirus that infects immature erythroid cells and causes aplastic crisis, fifth disease, and fetal death
Parvovirus B19
The disease caused by Parvovirus B19, characterized by a ‘slap cheek’ rash
Fifth disease
The size and shape of anelloviruses
~30 nm, icosahedral
The presence or absence of an envelope in anelloviruses
None (naked virus)
The genome structure of anelloviruses
Circular, single-stranded DNA, negative sense
The group of viruses included under anelloviruses
Torque teno viruses
The disease association of anelloviruses
No proven specific disease
The size of polyomaviruses
Small (45 nm)
The presence or absence of an envelope in polyomaviruses
None (naked virus)
The symmetry of polyomaviruses
Cubic symmetry, 72 capsomeres
The genome structure of polyomaviruses
Circular, double-stranded DNA
The type of DNA synthesis stimulated by polyomaviruses
Cell DNA synthesis
The slow-growing polyomavirus that causes progressive multifocal leukoencephalopathy
JC virus
The polyomavirus associated with nephropathy in transplant recipients
BK virus
The polyomavirus linked to Merkel cell carcinoma
Merkel cell virus
The primate polyomavirus that can also infect humans
SV40
The common name for papillomaviruses
Wart viruses
The HPV serotypes associated with cervical and anorectal cancer
HPV 16 and 18
The host and tissue specificity of papillomaviruses
Host and tissue specific
The ability of papillomaviruses to be grown in cultured cells
Cannot be grown in vitro
The size of adenoviruses
Medium (70–90 nm)
The symmetry of adenoviruses, consisting of 252 capsomeres with fibers
Cubic symmetry
The presence or absence of an envelope in adenoviruses
None (naked virus)
The genome structure of adenoviruses
Linear, double-stranded DNA
The site where adenoviruses replicate
Nucleus
The type of mRNA splicing patterns seen in adenoviruses
Complex splicing patterns
The body systems affected by adenoviruses
Mucous membranes, lymphoid tissue
The diseases caused by adenoviruses
Acute respiratory diseases, conjunctivitis, gastroenteritis
The virus family that includes Hepatitis B virus
Hepadnaviridae
The size of hepadnaviruses
Small (40–48 nm)
The shape of hepadnaviruses
27-nm icosahedral nucleocapsid with an envelope
The genome structure of hepadnaviruses
Circular, double-stranded DNA with a single-stranded gap
The site of hepadnavirus replication and DNA repair
Liver
The type of hepatitis caused by hepadnaviruses
Acute and chronic hepatitis
The size of herpesviruses
150–200 nm
The structure of the herpesvirus nucleocapsid
100 nm, cubic symmetry, 162 capsomeres
The presence or absence of an envelope in herpesviruses
Enveloped
The genome structure of herpesviruses
Linear, double-stranded DNA
The number of proteins contained in herpesvirus virions
More than 30
The cells where herpesviruses establish latency
Ganglial or lymphoblastoid cells
The ability of herpesviruses to establish latent infections and reactivate
Yes, latency and reactivation
The human herpesviruses
HSV-1, HSV-2, varicella-zoster, CMV, EBV, HHV-6, HHV-7, HHV-8
The largest DNA viruses
Poxviruses
The structure and shape of poxviruses
Brick-shaped or ovoid, complex structure
The size of poxviruses
220–450 nm long × 140–260 nm wide × 140–260 nm thick
The genome structure of poxviruses
Linear, covalently closed, double-stranded DNA
The type of polymerase contained in poxvirus particles
DNA-dependent RNA polymerase
The site of poxvirus replication
Cytoplasm
The type of lesions produced by all poxviruses
Skin lesions
The human pathogens in the poxvirus family
Smallpox, vaccinia, molluscum contagiosum
The animal poxviruses that can infect humans
Cowpox, monkeypox
