9.1 GI Flashcards
GI Bleed pt initial workup
2 large bore IVs CBC, Coags, T+C IVF PPI EKG NG tube
If cirrhotic:
Ceftriaxone
Octreotide
GI Bleed
-brisk vs slow bleeding: cc/h? and PRBC how often?
brisk: >2cc/hr, 1U PRBC q4h
slow: <0.5cc/hr, 1U PRBC qday
GI Bleed: what dx test to look for bleeding? after EGD negative
brisk bleed: angiogram (IR)
slow: tagged RBC
none: colonoscopy
bleeding stopped, colonoscopy sees nothing: pill cam
suspect Boerhaave
-what tests
gastrographin swallow. if neg then Barium. If neg then EGD
Esophagitis:
think what infections and their tx? (4)
Exam clues to each?
candida–nystatin, fluconazole. Thrush
CMV–ganciclovir/foscarnet. Immunosuppressed.
herpes–acyclovir/foscarnet. Oral ulcers.
HIV–HAART. AIDS is clue.
Esophagitis DDx causes, categories?
“PIECE” of the esophagus. Dx requires piece to bx.
Pill-induced Infxn Eosinophilic Caustic Everything else.
Esophagitis, pill induced.
- Which are notorious (3)
- tx
NSAIDs, Abx, NRTIs
-EGD to remove, time to heal. PPIs comfort
Pt in ED with drooling and odynophagia, after ingestion of battery acid or drain cleaner. What next
Caustic esophagitis.
EGD in 24h to eval severity
low severity: liquid diet, then solid in 24-48h
high severity: NPO 72h. high risk strictures, perf, fistulas, bleeding
Eosinophilic esophagitis
- classic vignette
- tx
- how to dx and to be aware of
- kid with asthma/exzema, with long hx dysphagia. Cause is food allergy!
- tx PPI, topical steroids
- EGD shows eosinophilia. However, GERD can cause this too. Must have pt on PPI for 6-8 wks, then re-bx to see eosinophils
GI bleeder with sytolic murmur, think what?
assoc: Aortic stenosis and AVMs
Esophageal cancers:
which are located where.
causes?
Squamous: upper 1/3. smoking/ETOH
Adenocarcinoma: lower 1/3. GERD
Achalasia tx
Heller myotomy 1st, unless poor surg candidate
then balloon dilation (risk perf)
Esophageal involvement of Scleroderma
-tx
This is relentless GERD! b/c LES can’t contract.
High dose PPIs to prevent esophageal CA
Esophageal spasm
-tx
CCB, Nitroglycerin
Female with dysphagia and anemia, think what?
Plummer-Vinson.
esophageal rings, webs, and Fe def anemia
-No tx, but screen for esophageal CA (higher risk)
Pt at clinic with new GERD sxs. What are alarm sxs?
what to do if alarm sxs?
odynophagia, dysphagia.
weight loss
N/V
anemia
If alarm, go straight to EGD.
Weird/rare peptic ulcers:
4
Curling–burns
Stress–ICU
Cushing’s–high ICP
ZE syndrome–refractory ulcers with diarrhea
PUD triple tx:
what if pen allergic?
amoxicillin (flagyl if pen allergy), clarithromycin, PPI
Duodenal vs gastric ulcer sxs
Duodenal ulcer pain relieved with eating. Gastric worse eating.
Duodenal ulcer pain occurs after meal.(acid released in duodenum). ‘Pain wakes from sleep.’
H Pylori tests (3)
1st dx: urea breath
confirm dx: EGD with bx
test eradication: stool Ag
ZE syndrome
-what tests (3)
suspect if refractory Ulcers+diarrhea. gastrin secreting tumor at pancreas
- Serum gastrin level (high)
- Confirm dx: Secretin stim test (gastrin increases)
- locate: SRS–somatostatin receptor scintigraphy, or CT
Gastroparesis
-tx, what to be careful
- prokinetics (metoclopramide/erythromycin)
- do EGD to make sure no physical blockage before Rx
Virchow’s node
supraclavicular node, first mets of gastric CA (signet ring CA)