14 Peds Flashcards
You suspect child has immunodeficiency
-what tests first
Start with these 2:
CBC Ig panel (quantitative levels of Igs)
Newborn management: TTN vs RDS
- what is diff
- how to tx
TTN: delayed clearing of lung fluid, mainly in C/S
- hyperexpanded/wet lung on CXR
- give O2, possible CPAP/intubation
RDS: preemie, lack of surfactant
- hypoextended lungs, atelectasis on CXR
- give surfactant, possible CPAP/intubation
Leukocyte adhesion def,
Chediak higashi
LAD: massive leukocytosis but no pus. Baby has delayed cord separation. Tx with BMT
Chediak (think train tracks). impaired microtubule polymerization. Albino, neuropathy, neutropenia
Ataxia-telangiectasia
-what assocs to rememeber
telangiectasias, ataxia, DNA repair, lymphoma, leukemia
Bilious vomiting in neonate
-DDx, how to dx and tx
4 to know. KUB to dx, all have double-bubble and:
- normal gas beyond: Malrotation
2/3. double bubble only: Annular pancreas (no Down’s) and Duodenal atresia (Down’s)
- Air fluid levels: Intestinal atresia from cocaine
Malrotation: Barium enema if colonic (dx, might also tx), Upper GI series if not colonic. Surgery if dying bowel
Sickle cell dz:
-what see on blood smear, other than sickled cells
Howell Jolly bodies, if older and you assume spleen autoinfarcted.
Premature, BPD
-tx
surfactant, steroids in mom antenatal.
-lung protective strategy (try to keep FiO2 and pressures low)
DiGeorge
-how present?
CATCH 22
cardiac abnl facies thymic absence (no T cells) cleft palate hypoCa (no parathyroid)
Neonatal jaundice, you see elevated conjugated Bili
-DDx (3), how to workup
think:
- obstruction (biliary atresia)–HIDA scan, U/S
- sepsis–WBC, Cx
- metabolic inborn
CGD
- what infxns
- dx
- tx
macrophages not working (catalase bugs): Staph, Aspergillus
Dx: normal CBC and Ig’s (WBCs just don’t work), negative nitro blue.
Tx: Daily Bactrim, bone marrow trans
Bronchiolitis
-who gets admitted (4)
spO2 <92
premature <34wks
age<3 mo
cardiopulm abnormality
APGAR
- what are they
- when to do
1 and 5 min Appearance: blue, acrocyanosis, pink Pulse: 0, <100, 100+ Grimace: none, high stim, regular stim Activity: none, flexion, resists extension Resps: none, irregular, strong
VACTERL
-how to check
Vertebral–XR
Anal–visual
Cardiac–Echo
Tracheal–NG tube down throat
Esophageal–
Renal–VCUG
Limbs
rash that is blanching vs non-blanching
-think what
Blanching means blood is still inside vessels, so hypervascularization or vasodilation
non-blanching means extravasation of blood through vessel wall. This is worse. Non-blanching is purpura/petichiae. eg think meningococcus, HSP, etc.
Premature, NEC
- dx
- tx
Premature in ICU has bloody BM
- do XR, see pneumatosis intestinalis
- NPO, IV Abx, TPN
- Surgery
why never take 1st temp rectaly?
imperforate anus. found on visual inspection
- upside down XR (babygram) to find end of pouch
- can fix now or colostomy to later
Check VACTERL
Neonate, bilious vomiting, KUB shows “ground glass” apperance
Meconium ileus, CF
Dissolve plug with gastrograpin enema
Measles vs rubella
-how to tell diff
Different prodome:
Measles: 4 C's Coriza Conjunctivitis Cough Koplik spots
Rubella: not as sick, prodrome of tender LAD, esp postauricular
Coin sign
foreign body aspiration, object pushes posterior
see only on lateral film
SCID
-what do they need
Think ‘Mega-AIDS:’
PCP and MAC ppx (bactrim and azithro)
gastroschisis, omphaloecele, what else not to confuse?
also Bladder extrophy–red, shining, wet with urine
omphalo”sealed”
MCC immunodef?
IgA def, 1/500
Newborn management/resuscitation
-describe
Minute 1: Stimulate infant to breathe and suction (primary apnea).
30 sec: assess pulse and breathing. If <100 or resp difficulty, do PPV or intubate
Min 1-5: APGAR and pulse ox. make sure HR>100 and resps good.
If HR 60-100 or resps not good, continue PPV
If HR <60, do chest compressions
If no improvement, Epi into umbilical vein
Min 5+: APGAR, continue resus if necessary.
Premature infant, 4 problems
BPD
ROP
IVH
NEC
Newborn management:
Meconium
-what to do
If meconium present but infant vigorous (HR>100, good resps, etc), then simple mouth/nose suctioning.
If infant poor tone, HR<100, bad resps: ET suctioning.
If pulse <60, shift to ventilatory support
Neonatal jaundice, you see elevated unconjugated Bili
-DDx and Workup tests (3)
3 tests: Coombs, Hgb, Retic ct
- Isoimmunization? (Rh dz, ABO dz)–Coombs test
- Hgb high? Blood transfusion from Twin-twin or maternal-baby delayed cord clamping
- Hemolysis? Retic high, then think genetic: spherocytosis, Pyruvate k def, G6PD
- All-, then think Breast milk jaundice