9. Oxygen delivery and hypoxia Flashcards
1
Q
Reduced ventilation e.g. brain injury
A
↓ PAO2
↓ PaO2
↓ CaO2
2
Q
Increased fluid barrier in the lungs (pulmonary
oedema)
A
↓PaO2
↓CaO2
3
Q
Damaged circulatory system
A
↓ CO
↓ DO2
4
Q
Increased tissue fluid barrier
A
↓ PtO2 (tissue PO2)
5
Q
DO2 equation
A
CaO2 xCO
6
Q
CaO2 equation
A
SaO2 x[Hb]x1.34x10
7
Q
SaO2 is proportional to
A
PaO2
8
Q
Hypoxic hypoxia
A
• PO2 of arterial blood reduced
9
Q
Anaemic hypoxia
A
• PaO2 normal but [Hb] reduced
10
Q
Stagnant or ischaemic hypoxia
A
• PaO2 and [Hb] normal but blood flow low
11
Q
Histotoxic or cellular hypoxia
A
• Tissue DO2 normal but cells cannot use O2 due to a toxic factor
12
Q
Altitude
A
Hypoxic hypoxia
13
Q
Trauma
A
Anaemic hypoxia
14
Q
Cardiac failure
A
Stagnant or ischaemic hypoxia
15
Q
Sepsis / poisoning
A
Histotoxic or cellular hypoxia