9) Osteoporosis Flashcards
Osteoporosis
Chronic, progressive disease characterized by low bone mass, decr bone strength, & incr fx risk
What is the most common metabolic bone disease?
Osteoporosis
What is OP the major cause of?
*Fx in elderly resulting in pain, disability, costly rehab, poor QOL, & premature death
True or False: OP occurs t/o the lifespan.
True
What happens to many pt’s w/OP-related fx’s?
Fx’s go un-dx’ed.
Qualities of OP in males:
- Less common
- Underdx’ed
- Underreported
- Higher m&m than women
- Major public health concern
Collagen
Protein that provides a soft framework
CaP
Adds strength to & hardens bone
Where is cortical bone located?
Shafts of long bones
Where is trabeculated bone located?
Spine, pelvis, & ends of long bones
Osteoblasts
Build up bone
Osteoclasts
Break down bone
Osteocytes
Sense mechanical strain & respond to this train by stimulating osteoblasts & osteoclasts to do their thing
What type of bone cell makes up about 95% of adult bone?
Osteocytes
Generalized OP
Involves the entire skeleton
Regional OP
Involves a limb or region
Localized OP
Involves only focal areas; Sometimes the result of prolonged immobilization
Primary OP
Bone loss associated w/biological changes that take place t/o the lifespan
*Type 1 & Type 2
Type 1 OP
Occurs in post-menopausal women bc of decr estrogen
Type 2 OP
Associated w/the aging process
Secondary OP
Occurs at any age 2° to medical conditions, metabolic/nutritional disorders, meds, & immobilization