11) Stroke Flashcards
CVA
Sudden loss of neurological fxn as the result of a disruption to blood flow resulting in tissue death
Ischemia
Decr blood flow resulting in tissue death
Thrombosis
Aggregation of platelets & fibrin in a cerebral artery resulting in occlusion
*Has a gradual onset & pt often awakes w/sx’s
Embolus
Thrombus originates elsewhere, breaks off, & travels through the bloodstream to a narrowing region
*Onset is abrupt & happens w/activity
Lacunar Infarct
Occlusion of small vessels
*Gradual onset
What is lacunar infarct associated w/?
HTN or DM
TIA
Sx’s are gone w/in24hrs
Ischemic Penumbra
Rim of mild-moderate ischemic tissue around the area of infarct
How long can an ischemic penumbra remain viable for & why?
Several hours bc of collaterals
What happens if reperfusion isn’t quickly established w/a penumbra?
Necrosis
What % of normal blood flow does the brain need to survive?
20-25%
Antiplatelet drugs
Aspirin, Plavix, & Aggrenox
Anticoagulants
Heparin, Coumadin, & Lovenox
What are statins?
Block the enzyme that produces LDL
Hypertensives
Beta-blockers & Ace-inhibitors
How to differentiate a beta-blocker from an ace-inhibitor
Beta-blockers end in “ol”
Ace-inhibitors end in “il”
Intercerebral Hemorrhage
Arterial bleeding into the brain
Does an intercerebral hemorrhage have a high or low mortality rate?
High
What accounts for 15% of all CVA?
intercerebral hemorrhage
Etiology of intercerebral hemorrhage
- Atherosclerosis weakens small arterial walls
- Sudden BP incr
- > 65y/o
Clinical manifestations of intercerebral hemorrhage
*Specific to region
*Sx’s incr as hematoma enlarges
Seizure activity is possible
What does intercerebral hemorrhage result in?
- Structural distortion
- Incr ICP
- Devo of severe edema causing a midline shift
Subarachnoid Hemorrhage
Blood in the subarachnoid space
Sx’s of subarachnoid hemorrhage
Sudden onset of:
- Severe HA
- Nausea
- Vomiting
- Syncope
- Neck pain
- Confusion
- Lethargy
- Coma
Causes of subarachnoid hemorrhage
- AVM
- Age
- Trauma
- Neoplasm
- Infection
- HTN
- Vascular malformation
- Smoking
- Alcohol
Subdural Hematoma
Tearing of bridging veins between the brain & dura bc of truma
Who is subdural hematoma especially common in?
The elderly
How do elderly pt’s w/subdural hematoma present?
W/cognitive decline