9- Neurology Flashcards
Add types of
Seizures
CNS
Central nervous system, responsible for: Thought Perception Feeling Autonomic body functions
PNS
Peripheral nervous system, responsible for:
Transmitting commands from brain to body and receiving feedback from the body
What are the parts of the brain (7)
“Oh please to find like that helps”
Occipital lobe Parietal lobe Temporal lobe Frontal lobe Limbic system Thalamus (Diencephalon) Hypothalamus (Diencephalon)
What are the parts of the Brain Stem
Mid brain
Pons
Medulla Oblongata
What are the parts of the PNS
Cranial nerves
Peripheral nerves
Parts of a neuron (5)
Cell body Axon Dendrite Synapse Neurotransmitter
Occipital lobe role
-Vision and storage of visual memories
Parietal lobe role
- Touch and texture
- Storage of tactile memories
Temporal lobe role
- Hearing and smell
- Language
- Storage fo sound and odor memories
Frontal lobe role
- Motor cortex- Voluntary muscle control, storage fo spatial memories
- Prefrontal cortex- Judgement and prediction of consequences, abstract intellectual functions
Limbic System role
- Basic emotion
- Basic reflexes (chewing, swallowing)
Thalamus (Diencephalon) role
-Prioritize signals to hone in on important messages
Hypothalamus (Diencephalon) role
- Emotions
- Temperature control
- Interface with endocrine system
Midbrain role
- LOC
- Home of reticular activating system (RAS), which controls arousal and consciousness
- Muscle tone and posture
Pons role
-Respiratory pattern and depth
Medulla oblongata role
- Pulse rate and BP
- Respiratory rate
Spinal cord role
- Reflexes
- Relay info to and from body
Cranial nerves role
-Special peripheral nerves that connect directly from brain to body parts, send information to the brain
Peripheral nerves role
-Receive stimulus to body, send commands to body
Neuron cell body role
Home to nucleus and site of protein synthesis
Axon role
Projection from cell body to other neurons or organs and sends messages
Dendrite role
Projection from cell body that receives signals from axons
Synapse
Gap between an axon and dendrite
Neurotransmitter role
Chemical released by synapse that helps make the connection between one neuron and another
Decorticating posturing
Effected part
Abnormal flexion, armors contracted towards chest
-Maybe damage to area directly below cerebral hemispheres
Decerebrate posturing
Effected part
Abnormal extension, arms extended outward, palms probated, wrists flexed
Damage is near the brainstem
What cranial nerves are responsible for airway control
Trigeminal
Glossopharyngeal
Vagus
Hypoglossal
What is trismus
Tightly clenched teeth
Myelin is what color; white or grey?
WHITE
What do unmyelinated axons control
Gross motor function
What do myelinated axons control and another name for them
Fine motor skills
Schwann cells
Nodes of Ranvier
Allow impulse to jump from node to node for more rapid conduction
What is the pre synaptic neuron
The end of one neuron
What is the post synaptic neuron
The beginning of a neuron
Reflex process
- Initiate in PNS
- Synapse with Interneurons in CNS
- Interneurons synapse with motor neurons
- Motor neurons send out axons
What provides blood to the brain
2 carotid arteries, 80% of blood to brain
2 vertebral arteries, for basilar artery
Circle of Willis
Encircles pituitary
-A back up if carotids are blocked
Cerebrum and its role
Largest portion of brain, has left and right hemispheres
Thought, personality, mood, memory, intelligence
Cerebellum and its role
In posterior fossa of cranium, closely related to brain stem and higher brain centers
Spatial coordination, fine motor movement, muscle tone
How to measure CPP
CPP = MAP - ICP
Normal CPP range
50-160 mmHg
Critical CPP range
Below 40
Unconscious patient means what
Provide an airway
What does Cushings triad identify and the signs of it
Early stages of increased ICP
Increased systolic pressure
Widening pulse pressure
BradyC
Abnormal respirations
Hyperpnea and causes
Rapid, regular, deep respirations
Causes- Stimulants, OD, exercise
Cheyne-Stokes and causes
Crescendo, decrescendo with apnea
Causes- Brain stem injury, pre death pattern
Biots/Ataxic and causes
Irregular with periods of apnea
Causes- Brain stem injury
What are hallmark signs of ICP
Cushing reflex Posturing Biots Apneustic Cheyne-Stokes Unresponsive with dilated pupils or anisocoria
Unreactive dilated pupils indicate what
Brain stem injury
What should be considered if pupils are constricted
Narcotic overdose
What does anisocoria indicate
Increased ICP
What is a conjugate gaze
Deviation of both eyes in the same directions
What is dysconjugate gaze
Deviation of eyes to opposite directions, brain stem conduction problem
What are the causes of Coma (AEIOUTIPS)
Alcohol/acidosis Epilepsy Infection Overdose Uremia Trauma Insulin Psychosis Stroke
What is a structural coma
-Causes
Focal (asymmetrical) signs
Rapid onset
Unresponsive pupils
- Trauma
- Intracranial bleed
- Tumor
Toxic metabolic coma
-Causes
Symmetrical signs, slow onset, present pupil response
Causes- Hypo/Hyperglycemia, Kidney/Liver failure, Postictal, anoxia
Coma management
ABC’s
No gag reflex = Intubate
BGL
Narcan
Ischemic stroke
From atherosclerosis or tumor, block blood flow to the brain
Develops slowly
Hemorrhagic stroke
From aneurysm, HTN, bleeding within the brain
Develops quickly and will get worse
Transient Ischemic Attack (TIA)
Last minutes to hours
Mini strokes
Same S/S as ischemic strokes, may improve though
Stroke S/S
- Unilateral weakness/paralysis of face, opposite side extremity
- Abnormal speech
- Headache
- Drooling
- Numbness of face
Can cause seizures
Cincinnati Stroke scale components
Facial droop
Arm drift
Speech
Stroke management
- ABC’s
- Head elevated 15 degrees
- BGL and vitals
- Fluid only if hypotensive
Seizure triggers
- Specific time of day
- Sleep deprivation
- Fever or illness
- Flashing lights
- Drugs/Alcohol
- Stress
- Menstrual cycle
- HypoGlycemia
- Specific foods
Focal seizure
Begins on one side of brain
Generalized seizure
Both sides of the brain
Motor seizure
Change in muscle activity
- Clonic = Jerking
- Tonic = Stiffness
- Loss of muscle tone = Atonic
- Automatism = Repetitive movement
Non-motor seizure
- Vitals change
- Behavior change
- Cognitive change
- Emotional change
- Sensory change
Focal onset seizure
Awareness vs Impaired awareness
Awareness- Most common, usually <2min
-At risk for head injury, brain infection, stroke, brain tumor
Impaired awareness- Pt unaware, aura before, includes automatisms, usually 1-2 minutes
-Same risks as awareness
Focal to Bilat Tonic Clonic
- Starts in one area on one side, then both sides
- Sometimes dont remember beginning of seizure
- Focal <1 min
- Tonic-clonic 2 to 3 min, but rare
Myoclonic seizure
Shock like jerking
Gelastic seizure
Imitates laughter
Dacrrtystic seizure
Imitates crying
Refractory seizure
Frequency and severity interrupts quality of life
- Different seizure types throughout the day
- Chronic problem
Tonic-Clonic seizures (Grand Mal) steps
- Loss of consciousness
- Tonic phase: Rigid
- Hypertonic: Ached back, rigid
- Clonic phase: Vfib in the brain
- Post seizure, muscles relax, nystagmus
- Postictal
Signs of Postictal phase
- Initially aphasic (unable to speak)
- Confused
- Emotional
- Tired
- Headache
- Gradual return to normal
Psuedoseizures
-Explain
The same as Tonic Clonic seizures however the root is psychogenic, most cases it is unintentional
-Usually display with “organized” movement
Absence seizures (Petit mal seizures)
Stops all activity and freezes up, last no more than several seconds, no postictal period, typically in children
Partial seizure
- Effect limited portion of the brain, can effect one part then spread
- Considered simple partial or complex partial
What is Jacksonian march
Seizure begins in one area (hand) and moves to the next (arm) then next (shoulder) and continues
Seizure management steps
- Determine concern for trauma, inline stabilization if suspect
- History
- Do not restrain or prevent movement, dont place anything in patients mouth
- Provide ventilation for >30 sec apnea
- Place padding on cot to prevent injury
Status epilepticus
-The goal
Seizure lasting more than 4-5 min or consecutive seizures without regaining consciousness in between
- It IS life threatening
- Can damage or kill neurons
-Stop the seizure and ensure ABC’s
Status epilepticus Treatment
Benzos
Airway
Sedate and paralyze for airway ONLY if needed
Seizures Physical exam (9)
- Head/neck/tongue trauma
- Swelling of gums (Chronic Dilantin therapy)
- Amnesia
- Pupils and cranial nerves intact
- Motor/Sensory coordination
- HypoT or Hypoxia
- Incontinence
- Automatisms
- Dysrhythmias
Syncope
S/S
Sudden/temporary loss of consciousness with accompanying loss of postural tone, possibly from life threatening dysrhythmia, stroke
-Typically a result of loss of blood flow to the brain
S/S- Warning of lightheaded, brief LOC, short focal Clonic phase, BradyC
ALS seizure management
- ABC’s
- Meds
- Diazepam (Valium) 5-10 mg
- Midazolam (Versed) 1-2.5 mg
- Lorazepam (Ativan) .5-2 mg
- BGL
- Constant reevaluation
Common home seizure meds
Phenytoin Valproic acid Clonazepam Gabapentin Phenobarbital
What is the Brachial plexus
A network of nerves located in the posterior neck
What parts make up the diencephalon
Thalamus, Hypothalamus, limbic system
Types of headaches (4)
Tension
Migraine
Cluster
Sinus
Tension Headache
- Cause
- S/S
- Treatment
From muscle contractions of face, neck and/or scalp
-Stress, noise, eye strain, poor posture
S/S- Dull, persistent, non-throbbing
Treatment- ASA, Acetaminophen, Ibuprofen
Migraine headache
- Cause
- S/S
- Treatment
Causes by dilation and constriction of blood vessels in brain from hormone imbalance, caffeine, altitude changes, various foods
S/S- Intense throbbing on 1 side, nausea, vomiting, visual disturbance, photophobia
Treatment- Phenergan (Promethazine) -Class: Antihistamine -Dose: 12.5-25 mg IV/IM -SFx: Fluctuations in BP and HR -Note: Solid IV line needed to avoid arterial occlusion Ondansetron (Zofran) -Class: Antihistamine -Dose: 4 mg
Cluster headache
- Causes
- S/S
- Treatment
Burst headaches that are severe and usually accompanied by severe pain around one eye, 30 min to 2 hrs
Causes- Histamine release
S/S- Uniorbital pain, tearing, nasal congestion
Treatment- Antihistamines, Corticos, Ca channel blockers
Sinus headaches
- Causes
- Treatment
Pressure behind face with pain in forehead, nose and eyes
Causes- Infections of sinuses
Treatment- Analgesics, antihistamines, antibiotics
“Thunder clap” Headache
Sudden intracerebral hemorrhage; CVA. Report worst headache of life followed by rapid deterioration
Brain Tumor (Neoplasm)
Mass in the cranial vault and can cause compression of the brain
Treatment- Analgesics for pain and benzos for seizures
Brain abscess
-S/S
Accumulation of puss in the brain from bacterial infection
S/S- Headache, fever, nausea/vomiting, seizures, ALOC
11 degenerative diseases
- Muscular dystrophy
- Multiple sclerosis
- Dystonia
- Parkinson’s disease
- Central Pain syndrome
- Bell’s palsy
- Amyotrophic Lateral sclerosis (ALS)
- Peripheral neuropathy
- Myoclonus
- Spina Bifida
- Polio
Muscular Dystrophy
S/S
Treatment
Inherited muscular disorder where muscle of the body degenerate
S/S- Waddle gait, bulky calves, progressive weakness, unable to eventually walk, usually dead before 20
Treatment- Supportive
Multiple Sclerosis
Autonomic condition where myelin of of brain and spinal cord are destroyed by the body, not fatal
S/S- Numbness, weakness, paralysis, slurred speech, visual changes, unstable gait, vertigo
Treatment- Mainly supportive
Dystonia
S/S
Treatment
Localized alterations in muscle tone creating spasms, fixed postures and strange movement. Can result from stroke, Parkinson’s, schizophrenia
S/S- Listed above
Treatment- Mainly supportive, Benadryl 25mg IV can help with spasms
Parkinson’s disease
S/S
Treatment
Decrease in dopamine, which helps muscles move smooth, from damage to ganglia nerve cells
-Progressive disease
S/S- (Postural instability, Tremor, Rigidity, Bradykinesia) Numbness, weakness, paralysis, visual changes, unstable gait, tremors, vertigo, rigid walking
Treatment- Mainly supportive
Central pain syndronme
S/S
Treatment
Infection or damage to Trigeminal nerve (V)
S/S- Severe pain (electrical shocks) and painful twitch to face, lips, cheek, gums on one side
Treatment- Mainly supportive
Bells Palsy
S/S
Treatment
Paralysis of face due to inflammation of the facial nerve (VII)
S/S- Eyelid, corner of mouth droop, possible numbness. S/S only in face
Treatment- Supportive
Amyotrophic Lateral Sclerosis (ALS)
S/S
Treatment
Very fatal degenerative disease of voluntary muscle neurons
S/S-Progressive weakness arms and legs, eventually swallowing and respiratory problems, peripheral to medial
Treatment- Supportive
Peripheral Neuropathy
S/S
Treatment
Group of conditions damaging peripheral nerves of the body
- Mononeuropathy, Single nerve damage-Trauma, infection
- Polyneuropathy, Multiple nerves damaged-Diabetes, GBS
S/S-Sensory/Motor impairment, numbness, burning, pain, muscle weakness
Treatment- Supportive
Spina Bifida
S/S
Treatment
Congenital defect where one part of vertebra does not form, allowing spinal cord to be exposed
S/S- Can develop small pouch on the back, S/S vary
Treatment- Supportive
Polio
S/S
Treatment
Infection that attacks the bodies nervous system, through feces
S/S-Mild infection to respiratory arrest, weakness, pain, muscle spasms, paralysis, inability to swallow
Treatment-Ensure patent airway
Myasthenia Gravis
S/S
Autoimmune disease, resulting in chronic muscle weakness and neurotransmitters dont work
S/S-Look like death, double vision, facial muscle problems
Guillain-Barré syndrome
S/S
Treatment
Immune system attacks portions of the nervous system resulting in nerve inflammation with progressive weakness and paralysis moving towards core of body
S/S- Recent infection, rapid progression of paralysis/tingling/numbness, toe to head paralysis pattern
Treatment- Supportive, ventilation if needed