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PTN Block 1, MUSC '13 > 9/5/13 > Flashcards

9/5/13 Flashcards

1
Q

In combination with local anesthetics, this drug prolongs the duration of action and decreases toxicity by reducing absorption

A

Epinephrine

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2
Q

What receptors does epinephrine act on

A

alpha 1 and 2, beta 1 and 2

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3
Q

Drug of choice during anaphylactic shock

A

Epinephrine (treats severe hypotension and bronchial constriction)

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4
Q

Epinephrine decreases insulin secretion because of this receptor

A

alpha 2

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5
Q

Drug used mainly for severe shock

A

Norepinephrine (no beta 2 receptors)

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6
Q

Which receptors does norepinephrine act on

A

alpha 1 and 2, beta 1

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7
Q

Phlebitis, tissue sloughing, arryhythmias, and increased myocardial oxygen demand are adverse reactions of this drug

A

Norepinephrine

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8
Q

Isoproterenol acts on which receptors

A

Beta 1 and 2

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9
Q

This drug is used to treat COPD/Bronchial constriction, heart block, acute heart depression, and Long Q-T syndrome

A

Isoproterenol

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10
Q

Albuterol acts on which receptors

A

Beta-2

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11
Q

Mainly used for bronchial constriction but also was once used for relaxation during premature birth

A

Albuterol

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12
Q

Dobutamine acts on which receptors

A

beta-1

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13
Q

What are the advantages of using dobutamine instead of epinephrine or norepinephrine?

A

Dobutamine can affect the inotropy of the heart without affecting the blood pressure that much

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14
Q

Major effect of this drug, which in higher doses binds to beta 1 receptors, is renal vasodilator

A

Dopamine

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15
Q

Adverse reaction to this drug includes rebond hyperemia, ischemic damage o nasal mucosae, hypertension, and urniary retention

A

Phenylephrine

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16
Q

Phenylephrine acts on which receptors

A

alpha 1

17
Q

Clonidine acts on which receptors

A

alpha 2

18
Q

Used to treat withdrawal symptoms and is also an antihypertensive drug

A

Clonidine

19
Q

This sympathomimetics drug is reuptake inhibitor for serotonin, NE, and dopamine

A

Cocaine

20
Q

This substance is found in beer and cheese, and these products cannot be ingested when MAO is inhibited

A

Tyramine

21
Q

This type of amphetamine-like drug is used to treat ADHD

A

methylphenidate

22
Q

How do amphetamine like drugs work?

A

They travel through the re-uptake transporters in the terminal and displace stored cathecolamine neurotransmitter from the vesicles

23
Q

A mixed sympathomimetic drug that is a decongestant, antihypotensive, and antiashmatic

A

ephedrine and pseudoephedrine

24
Q

Phentolamine is a competitive blocker of which receptors

A

alpha 1 and alpha 2

25
Q

This drug is used as a short term control of hypertension due pheochromocytoma and has adverse affects of tachycardia, postural hypotension, and GI irritation

A

phentolamine

26
Q

Phenoxybenzamine is a non-competitive, irreversible blocker of which receptors

A

alpha 1 and alpha 2

27
Q

This drug lowers the blood pressure and enhances the sympathetic reflex activity resulting in increased heart rate and contractile force. Adverse reactions include tachycardia, postural hypotension and nasal stuffiness

A

Phenoxybenzamine

28
Q

Prazosin (any zosin) is a competitive blocker of which receptors?

A

Alpha 1

29
Q

This drug reduces hypertension without the side effect of tachycardia, also can help relieve obstruction of urinary tract in BPH

A

prazosin (if alpha 2 is blocked, NE release is not inhibited and thus can lead to overstimulation of the heart. Prazosin is a selective alpha 1 blocker)

30
Q

Tamusulosin acts on this type of specific alpha receptor found in the prostate

A

alpha 1a

31
Q

Propranolol blocks these receptors

A

Beta 1 and 2 (first generation beta blockers)

32
Q

This drug treats arrhythmias, angina pectoris, hypertension, decreases MI mortality, migraines, and stage fright

A

Propranolol

33
Q

The adverse side effects of this drug include cardiac depression, asthma attacks, CNS depression, delayed response to hypoglycemia, and rebound angina pectoris

A

Propranolol

34
Q

Drug used for glaucoma that is similar to propranolol

A

Timolol

35
Q

Metoprolol blocks this type of receptor

A

beta 1 (second generation blocker)

36
Q

This drug is antihypertensive, antiarrhytimic, treats angina pectoris and CHF and does not precipitate asthma attacks

A

Metoprolol (esmolol in emergency settings)

37
Q

Third generation beta blocker that block beta 1 and 2, alpha 1 used to treat hypertension and CHF

A

Carvedilol

38
Q

This drug displaces NE from storage vesicles without releasing them into the synapse and can cause suicidal thoughts, used to treat hypertension

A

resperine

39
Q

Drug can cause transient hypertension after displacing and releasing NE from the storage vesicles in the presynaptic terminal

A

Guanethidine

PTN Block 1, MUSC '13 (6 decks)

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