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pharma A.DAM > 8. Muscarinic receptor blocking drugs > Flashcards

8. Muscarinic receptor blocking drugs Flashcards

1
Q

Tertiary tropines

A

Atropine
Scopolamine
Benztropine

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2
Q

Quartrenery tropines

A

suffix -tropium

Ipratropium
Tiotropium

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3
Q

Synthetic drugs with tertiary N

A

Procyclidine
Cyclopentolate
Tolterodine

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4
Q

Synthetic drugs with quaternary N

A

Propantheline

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5
Q

Others Muscarinic receptor blocking drugs

A

Oxybutynin

Butyl-scopolamine

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6
Q

Typs Muscarinic receptor blocking drugs

A

Tertiary tropines
Quartrenery tropines
Synthetic drugs with tertiary N / quaternary N
Others

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7
Q

Atropine

A 
Competitive M receptor antagonist
antidote for cholinergic agonist 
eye drops / bradycardia, grade I AV block / GI, bladder, urinary cramps 
Belladonna (jimson weed) 
2-3 hr mydriasis 7-10day DOA 
Lethal dose 100 mg, infant 2mg
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8
Q

Scopolamine

A

2-3 hr mydriasis 2-7day DOA
Large distribution
Lethal dose 500 mg
Antiemetic (motion sickness)

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9
Q

Benztropine

A

M1 antagonist

Parkinson’s disease

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10
Q

Ipratropium & Tiotropium

A

M3 antagonist
Bronchodilator for COPD
Asthma prophylaxis

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11
Q

Procyclidine

A

Parkinson’s disease

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12
Q

Cyclopentolate

A 
Short acting (3-6hr DOA) 
Ophthalmology
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13
Q

Tolterodine

A

M3

For overactive bladder

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14
Q

Propantheline

A

For smooth muscle spasm

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15
Q

Oxybutynin

A

M3

For urinary incontinence

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pharma A.DAM (9 decks)

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