10. Indirect sympathomimetics. Selective α1-agonists. Selective α2-agonists and drugs acting on the imidazoline receptors Flashcards
1
Q
Indirectly acting sympathomimetics
A
Tyramine Ephedrine Amphetamine Reuptake inhibitors MAO inhibitors
2
Q
α receptor agonists
A
Systemic & Loca
α1 & α2
3
Q
drugs acting on imidazoline receptors
A
clonidine
imidazolines
4
Q
Ephedrine
A
mixed sympathomimetic
5
Q
Amphetamine
A
Methylphenidate
MDMA
Methamphetamine
6
Q
Reuptake inhibitors
A
Cocaine
Tricyclic Antidepressants (TCA)
SNRi
SSNRi
7
Q
MAO inhibitors
A
Tranylcypromine
Moclobemide
Selegiline
Phenelzine
8
Q
Methylphenidate
A
ADHD treatment
9
Q
α1 selective agonist
A
Phenylephrine
10
Q
α2 selective agonist
A
Clonidine Guanfacine Methyldopa dexmedetomidin tizanidin
11
Q
Local use
A
selectivity is not important in local use
Nasal: Naphazolin, Phenylephrine
Ophthalmology: Phenylephrine
12
Q
Phenylephrine
A
↑BP
13
Q
Clonidine
A
↓ sympathetic tone
↓BP
also acts on I1 imidazoline R
14
Q
Guanfacine
A
Centrally acting antihypertensive drug
15
Q
Methyldopa
A
inhibits α2 autoreceptor
α-methyldopa becomes α-methylNE which binds α2 autoreceptor
