11. α-receptor antagonists

Question 1

α-receptor antagonists types

Answer 1

Non-selective α antagonists
Selective α1 receptor antagonists
Drugs with α blocking side effect

Question 2

Non-selective α antagonists

Answer 2

Synthetic compounds

Ergot alkaloids

Question 3

Selective α1 receptor antagonists

Answer 3

Generally less tachycardia from Non-selective α antagonists

Prazosin 
Doxazosin 
Terazosin 
Tamsulosin
Urapidil 
Labetalol

Question 4

Drugs with α blocking side effect

Answer 4

Antidepressants

Antipsychotics

Question 5

Synthetic compounds

Answer 5

Phenoxybenzamine

Phentolamine

Question 6

Ergot alkaloids

Answer 6

Dihydro-derivatives

Question 7

Prazosin

Answer 7

Short half life
Orally active
For chronic moderate HT and BPH
side effect postural hypotension

Question 8

Doxazosin & Terazosin

Answer 8

longer half life Prazosin

for HT and BPH

Question 9

Urapidil

Answer 9

α 1 antagonist, β antagonist

weak α2 agonist & 5-HT1A agonist

Question 10

Labetalol

Answer 10

also β antagonist

Question 11

Phenoxybenzamine

Answer 11

irreversible
long duration
for pheochromocytoma

Question 12

Phentolamine

Answer 12

reversible

for pheochromocytoma

Question 13

differences between Phenoxybenzamine & Phentolamine

Answer 13

irreversible & reversible

Question 14

Dihydro-derivatives

Answer 14

Ergotamine

Question 15

Ergotamine

Answer 15

vasoconstrictor and alpha adrenoreceptor antagonist