8- Epigenetics + RNA interference =)

Question 1

The binding of testosterone to an androgen receptor (AR) changes the shape of the AR. This AR molecule now enters the nucleus and stimulates gene expression.
Suggest how the AR could stimulate gene expression. (2)

Answer 1

• AR = transcription factor
• binds to DNA
• stimulates RNA polymerase

Question 2

What does a p values of 0.02 suggest about the data? (3)

Answer 2

• 0.02 → < 0.05 probablity of being due to chance
• significant
• reject H0

Question 3

Define what is meant by epigenetics. (2)

Answer 3

• heritable changes in gene function
• w/o change to DNA base seq