7.1 - Inheritance Flashcards

1
Q

Define genotype

A

The genetic constituition of an organism

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2
Q

Define phenotype

A

The expression of an organism’s genetic constituition, combined with its interaction with the environment.

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3
Q

What is an allele?

A

Different forms of a particular gene, found at the same locus (positon) on a chromosome. A single gene could have many alleles.

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4
Q

How many alleles per gene do diploid organisms carry?

A

2

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5
Q

What is meant b a dominant allele?

A

An allele whose characteristic will always appear in the phenotype, whether one or 2 are present.

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6
Q

What is meant by a recessive allele?

A

An allele whose characteristic oly appears in the phenotype if no dominant allele is present, meaning 2 must be present.

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7
Q

What is meant by codominant alleles?

A

2 dominant alleles that both contribute to the phenotype, either by shwing a blend of both characteristics or the characteristics appearing together.

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8
Q

What is meant by homozygous and heterozygous?

A

Homozygous = both alleles are dominant or both alleles are recessive.
Heterozygous = one allele is dominant, the other is recessive.

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9
Q

Define monohybrid inheritance.

A

Where one phenotypic characteristic is controlles by a single gene.

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10
Q

Draw a Punnett square to show a monohybrid cross with parental genotype of GG and gg.

A

Should have GG on top line and gg on the side.
All middle boxes should have Gg

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11
Q

What % of these offspring will express te characteristic determined by allele G?

reffering to flashcard 10

A

100%
All potential offspring genotypes are Gg meaning none of them will express the recessive allele.

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12
Q

Define dihybrid inheritance.

A

Where 2 phenotypic characteristics are determined by 2 different genes present on 2 different chromosomes at the same time.

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13
Q

What is meant by sex-linkage?

A

Where an allele is located on one of the sex chromosomes, meaning itsexpression depends on the sex of the inividual.

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14
Q

Why are males more likely to express a recessive sex-linkage allele?

A

Most sex-linked alleles are located on the X chromosome. Therefore males only get one copy of the allele, so will express this characteristic even if its recessive. Since females get 2 alleles, this is very likely.

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15
Q

Which parent do males inherit sex-linked characteristics from?

A

Their mother, since the Y chromosome can only come from their father. Therefore, if the mother is heterozygous for sex-linked alleles, she is a carrier and may pass on the trait.

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16
Q

What is meant by autosomal linkage?

A

Where 2 or more genes are locates on the same (non-sex) chromosome. In this case, only one hoologous pair is needed for all 4 alleles to be present. For genes that aren’t linked, 2 homologous pairs are needed.

17
Q

What is meant by epistasis?

A

Where 2 non-linked genes interact, with one gene either masking or suppressing the other gene.

18
Q

Define the 2 types of epistasis

A
  • Recessive epistasis = where 2 homozygous recessive alleles mask expression of another allele.
  • Dominant epistasis = where one dominant allele masks expression of multiple other alleles.
19
Q

What is the chi-squared test?

A

A statistical test to find out whether the difference between observed and expected data is due to chance or a real effect.

20
Q

What are the criteria for the chi-squared test?

A
  • Data placed in discrete categories
  • Largw sample size
  • Only raw count data allowed i.e not percentages
  • No data values equal 0
21
Q

How is a chi-squared test perfomed?

A

The formula results in a number, which is then compared to a critical value. If the number is greater than or equal to the critical value, we conclude there is a significant difference between the observed and expected data and that the results did not occur due to chance.

22
Q

How can we use a chi-squared test in relation to the content of this topic?

A

We can compare expected phenotypic ratios with observed ratios to test our understanding of how different genes and alleles are inherited.