71 entesitis-related arthritis, Flashcards

1
Q

What is enthesis related arthritis

A

It is a form of JIA

Involves inflammation of the joints and the enthesis ( spots where tendons and ligaments attach to bones)

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2
Q

What is the age of onset in enthesis related arthritis

A

9-12

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3
Q

Extraarticular manifestations of enthesis related arthritis

A

Acute anterior uveitis - by redness, pain, and photophobia

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4
Q

What are the characteristics of the enthesis related arthritis

A

More in male

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5
Q

What are the joint involvement in enthesis related arthritis

A

Often symetrical

Hips joints often affected- sacroiliac joint tenderness

lower back pain that starts insidiously, improves with exercise, and is associated with more than 30 minutes of morning stiffness or alternating buttock pain

Untreated sacroiliitis may progress to spondylitis

Few joints in the keg

_

Enthesis most common in knee ankles and bottom of the feet -
Tendon of the finger and toes and the toes look like sausages. - dactylitis
Small joints of the feet - tarsitis

May affect the spine and joints between base of spine - inflammatory lumbosacral pain
Leading to neck and back pain or stiffness

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6
Q

Treatment of enthesis related arthritis

A

Sacroiliitis may not respond to medications commonly used as first-line agents for JIA, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or disease-modifying antirheumatic drugs (DMARDs), and the disease may continue to progress along the axial skeleton. A subset of children with sacroiliitis will progress to spondylitis as adults, which is characterized by back pain, stiffness, and eventual fusion of the vertebra

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7
Q

Treatment of enthesis related arthritis

A

Sacroiliitis may not respond to medications commonly used as first-line agents for JIA, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or disease-modifying antirheumatic drugs (DMARDs), and the disease may continue to progress along the axial skeleton. A subset of children with sacroiliitis will progress to spondylitis as adults, which is characterized by back pain, stiffness, and eventual fusion of the vertebra

NSAID monotherapy may be appropriate for children with low disease activity
Indomethicin
Diclofenac 
Methotrexate DMARD/ sulfasalazine
Biological agents
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