7.1 Flashcards

1
Q

Cell divide defintion

A

produce 2 identical daughter cells

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2
Q

cell differentiate

A

stop dividing to specialize in structure and function

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3
Q

Cell division occurs when

A

mitosis

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3
Q

Cell die definition

A

Eliminates unnecessary cells during development and removes unhealthy cells

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4
Q

Interphase includes

A

G1,S, G2

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5
Q

G1

A

cell increases in size, prepares to replicate, has to be undamaged, and has enough resources available for the cell to keep growing

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6
Q

S

A

cell replicates DNA, 2 complete sets of chromosomes, monitored for replication errors

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7
Q

G2

A

cell continues to grow and prepare for division, chromosomes are fully replaced and contain other types of damages

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8
Q

CDK-cyclin

A

stimulating protein

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9
Q

p53

A

inhibitory protein

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10
Q

cyclin-dependent kinases

A

are enzymes that add phosphate to other proteins to activate or inhibit their function

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11
Q

proto-oncogenes vs oncogenes

A

are an accelerator to speed up a simulation with one allele and put the cell cycle into overdrive vs a break to slow it down with both alleles needing to be mutated to be affected

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12
Q

effect of mutated tumor suppressors

A

can cause loss of inhibition or both leading to uncontrolled cell division

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13
Q

density-dependent inhibition

A

relies on the contact between the surface protein of adjacent cells when they bind they send out signals for cell division like a container

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14
Q

a mutated oncogene is like a

A

gas pedal

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15
Q

a tumor suppressor is like a

A

brake

16
Q

difference between a proto-oncogene and an oncogene

A

proto is the normal gene and oncogene is the mutated gene

17
Q

is the mutated allele (oncogene) dominant or recessive?

A

dominant

18
Q

is the mutated allele of a tumor suppressor dominant or recessive?

A

recessive

19
Q

what are the three buckets to categorize cancer?

A

cell growth & survival, cell fate, genome maintenance

20
Q

Does DNA polymerase make mistakes during DNA replication?

A

yes every billion but the proofreading system reads mistakes and fixes errors unless there is a mutation that occurs in the genes that encode the proofreading system could lead to mutations at a rapid rate