[7] Stroke in Children Flashcards
Stroke in the young refers to what demographic of people?
Patients
Most common type of Pediatric Stroke
Arterial Ischemic Stroke
Differentiate Acute Ischemic Stroke from Transient Ischemic Attack
Neurologic symptoms present with neuroimaging evidence of a cerebral infarction
(Time frame being more than 24 hours is not strictly followed anymore)
In what pediatric group is the incidence of stroke most common?
Neonatal Period
Describe the pathophysiology of an arterial dissection
Tear of a layer of the blood vessel wall causing a clot formation that is dislodged and occludes another vessel leading to the stroke event
What causes moya-moya?
Created by collateral vessels that develop secondary to a progressive, proximal, non-inflammatory, occlusive vasculopathy of the distal ICA
What diseases are associated with Moya-moya?
- Down Syndrome
- Neurofibromatosis
- Sickle cell disease
This virus is associated with a cerebral angiopathy
Varicella
Examples of Coagulation Inhibitors
Protein C
Protein S
Anti-Thrombin
Examples of Coagulation Proteins
Activated Protein C Resistance (APCR)
Prothrombin Gene Mutation
Most common infectious etiology of CNS Infections in PGH
TB Meningitis
A mother with recurrent miscarriages may have this syndrome
Anti-phospholipid Antibody Syndrome: A hypercoaguable state that may be passed onto the infant
If patient is unable to take aspirin, what should be taken instead?
Clopidogrel
Good way to differentiate an Ischemic from a Hemorrhagic Stroke
Patients with ischemic stroke present with dense plegia (0/5) but are awake and can talk with slurred speech.
Patients with hemorrhagic stroke come in with severe headache with decreased sensorium or stuporous.
